Reduced vision throughout early childhood is typically due to errors of refraction. Objective: To compare refractive status in children (age 5 to 15 years) checked with subjective refraction under cycloplegia versus post mydiatric test (PMT). Methods: Comparative cross-sectional study was conducted in pediatric ophthalmic clinic of College of ophthalmology and Allied vision sciences /Mayo hospital Lahore including 120 non-pathological eyes of 60 subjects. Individuals with nystagmus and deviation of eyes were excluded. Power of SE (P1) was taken as proposed number of glasses to be dispensed. After three days PMT was done and prescription of glasses with BCVA (P2) was noted and prescribed. At PMT (P2-P1) was noted and evaluated. All data entered and analyzed by using SPSS-23. P-value equal or less than 0.05 was taken as significant. Results: Among 120 eyes (n=120), the distribution of myopia was 57.5% and hyperopia was 42%. The mean age of 60 individuals (female: 35% and male: 65%) was 9.47 ± 2.50 years. Among 120 eyes (n=120), the distribution of myopia was 57.5% (n = 69 eyes) and hyperopia was 42% (n = 51 eyes). Interclass correlation: Two-way mixed effects model where people effects are random and measures effects are fixed. a. The estimator is the same, whether the interaction effect is present or not. b. Type C intraclass correlation coefficients using a consistency definition. The between-measure variance is excluded from the denominator variance. c. This estimate is computed assuming the interaction effect is absent, because it is not estimable otherwise.
Purpose: To determine the difference between mean retinal nerve fiber layer (RNFL) thickness in myopic eyes (up to -6.00D) and normal eyes. Study Design: Descriptive observational study. Place and Duration of the Study: Eye department of Mayo hospital Lahore, from February 2019 to April 2019. Methods: We compared the mean RNFL between 58 myopic eyes (up to -6.00 D) and age matched 60 normal eyes. The age of the participants was between 12 to 42 years. Complete ocular examination was done and RNFL thickness was measured by using Optical coherence tomography (NIDEX RS-33.0, software-ex 1.5.2).Data was analyzed by independent sample t-test by using SPSS; with P < .05 as significant. Results: The mean difference among these groups was 5.852 µm with (SE: 1.929). Mean RNFL thickness in myopic group was (95.93 ± 10.158µm) with (SE: 1.334). The result for mean RNFL thickness in myopic eyes was distributed normally as P < .03. Mean RNFL in normal group was (101.78 ± 10.774 µm) with (SE: 1.391), and the result of mean RNFL thickness measured in normal eyes was not distributed normally as P < .20. The results showed that there is a statistically significant difference between mean RNFL thickness measured in normal versus myopic eyes as (P < .003). Conclusion: There is a significance difference between mean RNFL thickness between myopic eyes and normal eyes as measured by OCT. Careful interpretation of RNFL data in myopic eyes is recommended to avoid misdiagnosis with glaucoma. Key Words: Retinal Nerve Fiber Layer thickness, Myopia, Optical Coherence Tomography.
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