Rhinophyma is a slowly progressive, benign dermatological disorder of the nose. The most widely accepted theory is that rhinophyma is the end stage of chronic rosacea. The primary reason for its excision is cosmetic deformity. Many treatment modalities have been described, including CO(2) laser. This method provides a very dry surgical field, which allows the sculpting of the hypertrophic areas. Pulsed dye laser (PDL) is a safe and effective treatment, resulting in a significant improvement in erythema, telangiectases, symptoms and quality of life. We report the case of a 63-year-old Caucasian man with a 2-year history of rapid progression rhinophyma. The patient was submitted to five CO(2) laser sessions, followed by three PDL sessions. Favourable re-epithelization of the surfaces treated with CO(2) laser was achieved within a very short period of time. PDL post-treatment purpura lasted a medium of 12 days. After 12 months of follow-up the patient remains without evidence of relapse. To our knowledge, this is the first case described of treatment using a combination of the CO(2) laser and PDL.
Necrobiosis lipoidica is a rare granulomatous and inflammatory disease. Its management is particularly difficult when ulceration is present. The authors describe the clinical case of a 65-year-old female patient with necrobiosis lipoidica, who had been submitted in the past to several topical and systemic treatments with little or no improvement. She started treatment with subcutaneous etanercept and showed significant improvement without adverse events until today. The aim of this article is to report a valid and efficient alternative treatment to recalcitrant cases.
The study of the Sun is an area still open in several topics of astrophysics, in a field that has seen an expansion in recent years - therefore, it is critical that collected data is thoroughly traceable and accurate to be used in new study cases or predictive models. A ground based, portable, optimized system, consisting of a Schmidt-Cassegrain telescope coupled to a refractor telescope acting as a pointing telescope, is being designed to provide high resolution imaging of smaller areas on the Sun’s surface, being able to obtain disk-resolved, high spectral resolution data, at a relative low cost (compared to large consortium developed instruments). The light collected by the telescope will be fibre-fed to a spectrograph - the injection of light in the fibre is critical and requires an imaging sensor to aid the light guiding process. The goal of the present work was to explore the best candidates for the image sensors, their architectures, requirements, and constraints, as well as their expected performance range and signal noise. The trade-off analysis between CMOS and CCD based sensors was made and it was concluded, that for the intended application, either type of architecture is admissible, provided the sensor is within desired parameters.
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