No abstract

Durian (Durio zibethinus Murr.) telah lama digunakan sebagai salah satu pengobatan tradisional untuk mengobati berbagai macam penyakit, termasuk untuk penderita diabetes mellitus. Penelitian ini bertujuan untuk menentukan aktivitas ekstrak etanol durian dalam menurunkan kadar glukosa darah pada mencit yang diinduksi aloksan dosis 125 mg / kgBB dan diberi beban glukosa 20%. Sebanyak 36 ekor mencit dibagi menjadi 6 kelompok perlakuan. Kelompok I sebagai kontrol sehat, kelompok II diinduksi dengan aloksan dan diberikan NaCMC 1% (kontrol negatif), kelompok III diinduksi dengan aloksan dan diberikan Acarbose® (kontrol positif), kelompok IV diinduksi dengan aloksan dan diberikan ekstrak etanol akar durian (EDR), ekstrak klika (ESB) dan ekstrak daun (EDL) dosis 125 mg / kgBB, kelompok V diinduksi dengan aloksan dan diberikan ekstrak etanol akar durian (EDR), ekstrak klika (ESB) dan ekstrak daun (EDL) dosis 250 mg / kgBB, kelompok VI diinduksi dengan aloksan dan diberikan ekstrak etanol akar durian (EDR), ekstrak klika (ESB) dan ekstrak daun (EDL) dosis 500 mg / kgBB. Pengukuran kadar glukosa darah dilakukan sebelum induksi alloxan (t-0), 3x24 jam setelah induksi (t-3), dan setiap 30 menit setelah pemberian perlakuan ekstrak dan larutan glukosa hingga menit ke-180 (t30, t60, t90, t120, t150 dan t180), yang dilakukan pengukuran menggunakan alat glukometer (Nesco®). Persen penurunan kadar glukosa darah yang paling tinggi ditunjukkan setelah menit ke-180 pada kelompok EDR dengan dosis 125 mg / kgBB, ESB dosis  250 mg / kgBB dan EDL dosis 500 mg / kgBB yaitu  sebesar 50,60%, 105,62%, dan 62,97%.

ABSTRAKSalah satu cara reproduksi tumbuhan Asystasia gangetica (L.) T. Anderson adalah menggunakan reproduksi vegetatif melalui stek. Tujuan penelitian ini adalah untuk mengevaluasi pengaruh perbedaan umur terhadap pertumbuhan dan produksi stek A. gangetica. Penelitian dilakukan dengan rancangan acak lengkap 3 perlakuan umur panen (50, 70 dan 90 hari) dengan 24 kali ulangan. Parameter yang diamati adalah tinggi tanaman, jumlah ranting, berat batang, jumlah stek dan diameter stek pada saat panen. Data dianalisis dengan ANOVA dan uji lanjut LSD menggunakan software Ri386 versi 3.3.2. Hasil penelitian menunjukkan bahwa pertumbuhan tinggi tanaman A. gangetica cenderung membentuk pola sigmoid berupa polynomial berderajat tiga. Berdasarkan penelitian ini, tanaman berumur 90 hari memiliki tinggi (128,1±12,3) dan berat batang terbaik (156,7±18,6) serta menghasilkan jumlah stek yang terbanyak (17,1±4,25) dan diameter stek terbesar (4,3±0,7). Produksi stek A. gangetica berasal dari ranting primer dan sekunder.Kata kunci: Asystasia gangetica, pertumbuhan, produksi stek, umur panen

During the Covid-19 pandemic, which has not yet ended, the business of selling honey is a type of business that is able to survive and even increase its market. The trend of selling honey in the era of the Covid-19 pandemic is quite stable and has the potential to be a good source of income because honey can be used as medicine and can increase the body's immunity. Fitorajo Bee Farm is a UMKM engaged in bee cultivation which is located in Pinang City, South Labuhanbatu Regency, North Sumatra Province with original honey bee products packaged in plastic bottle containers. The marketing system carried out by Fitorajo Bee Farm is carried out through word of mouth, Facebook social media, or through the WhatsApp application. Seeing the promising potential of the honey business in the Covid-19 pandemic era, and in order to reach a wider market, Fitorajo Bee Farm should improve and innovate by adopting e-commerce technology. Conventional marketing, which so far only reaches consumers on a limited scale, must be changed with a marketing system that can reach consumers from any corner. The purpose of this research is to build a marketing media for Fitorajo Bee Farm honey bees by implementing web-based e-commerce. The system development method used is the waterfall model, while the programming language used is PHP framework codeigniter with MySQL DBMS. The results showed that the codeigniter framework and MySQL DBMS can be applied to build e-commerce web-based honey bee marketing media.

This study was aimed to prepare polyeugenol with high molecular weight and to evaluate its antibacterial and antioxidant activities. First, polyeugenol was synthesized from eugenol in the presence of H2SO4-CH3COOH (4:1) as catalyst. The synthesized polyeugenol was weighed by using viscometer, revealing its high molecular weight of (7.76–21.9) × 105 g/mol. Furthermore, the antibacterial activity of the polyeugenol was conducted against Staphylococcus aureus and Escherichia coli bacteria. It was conducted by applying well diffusion method at 1, 2, 3, 4 and 5% concentrations to observe inhibition zones, in which the tests showed that the antibacterial activity of the polyeugenol against S. aureus were 17.42, 17.76, 18.79, 21.42 and 22.55 mm, while those against E. coli were 15.87, 17.23, 17.56, 18.24 and 19.21 mm, respectively. In short, these results indicated a strong antibacterial activity. Then, tests on antioxidant activity against free radical DPPH (2,2-diphenyl-1-pycrylhydrazyl) gave the IC50 value of 80.47 µg/mL, indicating a strong antioxidant activity. Therefore, the polymer synthesized in this work has a high potential to be applied in various biomedical applications.

Plant Lime (Citrus aurantifolia) and Plant Kaffir Lime (Citrus hystrix) including Rutacea family. Part of the plant lemon and lime are used as a drug other than fruit and leaves that can be used as medicine. This study aims to determine the antibacterial activity infuse lime leaves and lime leaves. Examination of the characteristics simplicia macroscopic examination. Phytochemical screening of compounds includes examining alkaloids, flavonoids, tannins and infuse saponin. Ekstrak conducted using distilled water solvent. Test of antibacterial activity against Escherichia coli bacteria carried by the agar diffusion method using a paper disc. Results obtained from macroscopic examination for lime leaves are fresh leaves leaf-shaped single smooth surface and the lower surface of the leaves are light green, the dark green upper surface. If torn, lime leaves produce coarse fibers. The leaves are small with a width of 3-5 cm. For lime leaves are fresh leaves, leaf litter pinnate compound leaves one. Child leaf blade oval to oblong, base rounded or blunt, the blunt end up pointed, 8-15 cm long, 2-6 cm wide, the upper surface colour some what shiny dark green, light green below the surface. Results of phytochemical screening simplicia powder lime leaves and lime leaves that contain a class of alkaloids, flavonoids and tannins. Antibacterial activity test results showed that there were differences between the antibacterial infusion lime leaves and lime leaves kaffir lime leaves which are more effective against the bacteria Escherichia coli compared kaffir lime leaves.

AbstractThree stigmastane steroids: 6-hydroxystigmast-4-en-3-one (1), stigmast-4-en-3-one (2), and 3-hydroxystigmast-5-en-7-one (3) were successfully isolated from the acetone extract of Dryobalanps oblongifolia stem bark. The structural determination of isolated compounds was carried out on the basis of data analysis of NMR and MS spectra. In order to identify the antiplasmodial activity, the isolated compound was put to test against Plasmodium falciparum 3D7. Antiplasmodial activity of the isolated compounds showed that the IC50 values of 6-hydroxystigmast-4-en-3-one were 37.29 μg/mL while the IC50 values of stigmast-4-en-3-one were 43.54 μg/mL and the IC50 values of 3-hydroxystigmast-5-en-7-one were 13.34 μg/mL (chloroquine phosphate was used as a positive control, IC50 0.006 μg/mL). Judging from the results, the isolated compounds were proven to demonstrate mediocre antiplasmodial activity. Compound (3) indicated a better antimalarial activity than compound (1) and (2), even though there was no satisfactory activity that indicated its ability to combat chloroquine. Therefore, it might not be developed as an antimalarial drug.

Tujuan penelitian pengembangan ini adalah menghasilkan bahan ajar tulis arab melayu untuk mahsiswa jurusan Pendidikan Guru Madrasyah Ibtidaiyah dengan isi, penyajian, bahasa serta kegrafikan yang layak dan efektif untuk pembelajaran. Penelitian ini menggunakan model penelitian Ethnography dimana penelitian Ethnography ialah penelitian terhadap budaya kelompok melalui wawancara dan observasi. Sampai saat ini bahan ajar bahasa arab yang berkembang dan digunakan secara luas di Indonesia secara umum adalah bahan ajar yang digunakan di madrasyah dan MIN/SD. Jika bahan ajar merupakan hasil pengembangan yang jumlahnyatidak begitu banyak.Selagi tuntutan inovasi dan pengembangan bahan ajar bahasa arab, dewasa ini terus bergulir, sejalan dengan dinamika perkembangan ilmu pengetahuan dan teknologi. Selain itu, permintaan akan bahan ajar bahasa arab yang menggunakan bahasa Indonesia sebagai bahasanya berkembang di sebagian besar siswa pengantar, terutama mereka yang memiliki pendidikan umum latar belakang.Dengan demikian, salah satu kebutuhan yang harus dimiliki guru dalam melaksanakan tugas ialah mengembangkan bahan ajar. Pengembangan bahan ajar seorang guru itu penting agar pembelajaran lebih efektif, efesien dan tidak menyimpang dari kompetensi yang dicapai.