Inflammation is a key feature of atherosclerosis and its clinical manifestations. The leukocyte count is a marker of inflammation that is widely available in clinical practice. This paper reviews the available epidemiologic evidence for a relationship between the leukocyte count and coronary heart disease (CHD). Numerous epidemiologic and clinical studies have shown leukocytosis to be an independent predictor of future cardiovascular events, both in healthy individuals free of CHD at baseline and in patients with stable angina, unstable angina, or a history of myocardial infarction. This relationship has been observed in prospective and retrospective cohort studies, as well as in case-control studies. It is strong, consistent, temporal, dose-dependent, and biologically plausible. The relationship persists after adjustment for multiple CHD risk factors, including smoking. Elevated differential cell counts, including eosinophil, neutrophil, and monocyte counts, also predict the future incidence of CHD. Leukocytosis affects CHD through multiple pathologic mechanisms that mediate inflammation, cause proteolytic and oxidative damage to the endothelial cells, plug the microvasculature, induce hypercoagulability, and promote infarct expansion. In summary, leukocytosis has been consistently shown to be an independent risk factor and prognostic indicator of future cardiovascular outcomes, regardless of disease status. The leukocyte count is inexpensive, reliable, easy to interpret, and ordered routinely in inpatient and outpatient settings. However, its diagnostic and prognostic utility in CHD is widely unappreciated. Further studies are needed to assess the true impact of leukocytosis on CHD, compare it with other inflammatory markers such as C-reactive protein and lipoprotein phospholipase A(2) levels, and promote its use in CHD prediction.

The current crises in Syria has led to a number of Britons travelling abroad to fight with groups such as Isis. Capitalising on this growth, Isis are now increasingly fighting an online cyber war, with the use of slick videos, online messages of hate and even an app that all aim to radicalise and create a new generation of cyber jihadists. These modern day tools are helping Isis spread their propaganda and ideology to thousands of online sympathisers across the world. Indeed, the group has actively been using social media sites such as Twitter, Facebook and YouTube to recruit new would be members. This is being done through images and the streaming of violent online viral videos filmed and professionally edited that are targeting young and impressionable people. Portraying a glamorised and 'cool' image, Isis fighters are beginning to act as the new rock stars of global cyber jihad. The Internet therefore is becoming the virtual playground for extremist views to be reinforced and act as an echo chamber. This study analysed 100 different Facebook pages and 50 Twitter user accounts which generated over 2050 results and helped the author create a typology of seven key behaviour characteristics and motivations. The findings in this study confirmed the author's original hypothesis, i.e. online hate is being used by groups such as Isis for a variety of reasons such as recruitment and propaganda. Moreover, this material is coordinated and controlled by Isis as a means for publishing and sending out key messages.

The Woolwich attack in May 2013 has led to a spate of hate crimes committed against Muslim communities in the United Kindom. These incidents include Muslim women being targeted for wearing the headscarf and mosques being vandalized. While street level Islamophobia remains an important area of investigation, an equally disturbing picture is emerging with the rise in online anti-Muslim abuse. This article argues that online Islamophobia must be given the same level of attention as street level Islamophobia. It examines 500 tweets from 100 different Twitter users to examine how Muslims are being viewed and targeted by perpetrators of online abuse via the Twitter search engine, and offers a typology of offender characteristics.

online and offline anti-Muslim hate crime. We draw on our different experiences of conducting research on anti-Muslim hate crime, using two independent research projects in order to consider the affinity between online and offline anti-Muslim hate crime. We argue that, in reality, online/offline boundaries may be more blurred than the terms imply. For victims, it is often difficult to isolate the online threats from the intimidation, violence and abuse that they suffer offline. Moreover, victims often live in fear because of the possibility of online threats materialising in the 'real world'. We conclude that there is a continuity of anti-Muslim hostility in both the virtual and the physical world, especially in the globalized world.

The aim of this article is to examine the new Prevent Strategy 2011 in the United Kingdom and critically analyze its impact upon British Muslim communities. The U.K. government's controversial Prevent Strategy 2011 has come under fierce opposition, with critics arguing that it will not actually prevent extremism but risks labeling the Muslim community as a “suspect” community. Following the British government review of counterterrorism policies and strategies in 2010, the article examines the key question: Will the new Prevent policy actually work? Recent studies show that previous Prevent policies have risked alienating the Muslim community (Kundnani). Indeed, the new Prevent Strategy 2011 also has the risk of the depoliticization of Muslim communities from wider civic society and risks creating a mosaic for extremist ideologies. The article argues that, in practice, Prevent is not particularly efficacious, and that the new strategy risks further marginalizing and stigmatizing Muslim communities. Related Articles Related Media BBC News. . “State Multiculturalism Has Failed, Says David Cameron.” http://www.bbc.co.uk/news/uk‐politics‐12371994 BBC News. . “Funding Cut for Extremist Groups in Terrorism Review.” http://www.bbc.co.uk/news/uk‐13678635 BBC Radio 4. . “The Report: Extremism in the UK.” http://www.bbc.co.uk/programmes/b0132p8m El objetivo de este artículo es examinar la nueva Estrategia de Prevención 2011 (Prevent Strategy 2011) en el Reino Unido y analizar críticamente su impacto en las comunidades musulmanas británicas. La controversial Estrategia de Prevención 2011 del gobierno del Reino Unido ha sido objeto de una fuerte oposición, con críticos afirmando que no prevendrá el extremismo y se arriesgará el encasillar a la comunidad musulmana como una comunidad “sospechosa.” Luego de la modificación del gobierno británico de sus políticas y estrategias contra el terrorismo del 2010, este artículo examina la pregunta clave: ¿funcionará la nueva política de prevención? Estudios recientes muestran que políticas de prevención anteriores han corrido el riesgo de alienar a la comunidad musulmana (Kundnani). En efecto, la nueva Estrategia de Prevención 2011 también corre el riego de despolitizar a la comunidad musulmana de la sociedad civil y se arriesga a crear un mosaico de ideologías extremistas. Este artículo sostiene que en la práctica, Prevención 2011 no es particularmente eficaz y que la nueva estrategia expone a una mayor marginalización y estigmatización de las comunidades musulmanas.