-The aim of this study is to develop the POGIL (Process Oriented Guided Inquiry Learning) strategy of acids and bases concepts based on intertextual learning. The strategy was designed to assist students mastery concepts by interrelating the chemistry phenomena and acid-base concepts on three level representations: macroscopic, submicroscopic, and symbolic. The development process was initiating by curriculum analysis, developing three level representations of acid-base concepts, designing POGIL strategy intertextual-based, preparing instrument to measure students's mastery concept, and POGIL aplication in a limited class. All instruments were judged by the experts (chemistry lecturers and teachers) in term of content validity. The results were considered valid by all validators with some improvements based on the validator's suggestions and expertise.
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