Contrary to ECG, unshielded MCG reveals significant differences between normals and symptomatic patients with and without relevant stenoses using current density reconstruction during repolarization at rest. This method might be a suitable noninvasive tool for the management of patients with chest pain.
SummaryBackground: The noninvasive detection of coronary artery disease (CAD) remains a clinical challenge. Magnetocardiography is a completely noninvasive method that permits the registration of cardiac electrical activity at multiple sites in a plane above the chest cage without the need for electrodes. In contrast to the electrocardiogram (ECG) which suffers from boundary effects and a variety of potential artifacts (electrode placement, etc.) the MCG is unaffected by such impediments as the magnetic field is unaltered by surrounding tissues.Hypothesis: Magnetocardiography with a newly developed single-channel system in an unshielded setting should be a better qualitative diagnostic tool than the standard ECG for the detection and assessment of CAD.Methods: In all, 52 patients with angiographically documented CAD and unimpaired ventricular function as well as 55 controls were included in this study. A standard 12-lead ECG was obtained in all subjects. The MCG recordings were taken from 36 positions under resting conditions. From these, current density vector maps were generated during the ST-T interval. Each map was then classified using a classification system with a scale from 0 (normal) to 4 (grossly abnormal).
Unshielded four-channel MCG reveals obvious changes in the course of successful PCI on the basis of CDV map reconstruction during repolarization. The method seems to be suitable for the follow-up of patients after PCI.
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