Purpose To report long-term visual and refractive results of small-incision lenticule extraction (SMILE) in treatment of high myopia. Materials and Methods Medical records of patients who underwent SMILE for surgical correction of myopia or myopic astigmatism were retrospectively reviewed. Only patients with a preoperative spherical equivalent of subjective manifest refraction (SE) ≥ 6 D and a postoperative follow-up of 5 years were included in the study. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and SE were analyzed preoperatively and at 1-, 3-, and 5-year postoperative periods. Results Thirty-seven eyes of 37 patients were included in the study. The mean attempted SE was −7.47 ± 1.10 D (range −6.00 to −10.00 D). At the 5-year visit, the mean difference between achieved and attempted SE was −0.43 ± 0.47 (0.50 to −1.25 D). Mean postoperative UDVA and CDVA were 0.20 ± 0.18 and 0.06 ± 0.08 logMAR, respectively. At the 1-year visit, 70% and 97% of the eyes were within ±0.50 D and ±1.00 D of the intended correction. At the 5-year follow-up, 59% and 92% percent of the eyes were within ±0.50 D and ±1.00 D of the intended SE, respectively. At the 5-year visit, the efficacy index was 0.89 ± 0.26 and the safety index was 1.16 ± 0.20. Fifty-four percent of the eyes gained one or more lines of CDVA. Conclusion SMILE with an intended correction of up to a spherical equivalent of 10 D is safe and effective. However, there is regression of the refractive effect over extended follow-up.

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To the authors' knowledge, this study is the first to evaluate the long-term outcomes of the Eyecryl posterior chamber pIOL for high myopia. According to 5-year results, it is safe.

Purpose: To evaluate the changes in retinal microvasculature in eyes with anterior uveitis (AU) using optical coherence tomography angiography.Methods: Foveal avascular zone (FAZ) of super cial capillary plexus (SCP) and deep capillary plexus (DCP), vessel density (VD) of SCP, DCP, and choriocapillaris, and central macular thickness (CMT) and central foveal thickness (CFT) were calculated from 34 healthy and 41 uveitic eyes. The parameters were compared between the two groups.Results: The deep FAZ was signi cantly lower in the eyes with AU during the attack than after recovery and the control group (p=0.001 and p=0.003, respectively). The VD in deep capillary plexus (DCP) in eyes with AU during the attack was signi cantly higher than the control group (p=0.048). The VD in the foveal sector of DCP in eyes with AU during the attack and after recovery was signi cantly higher than the control group (p=0.001 and p=0.031, respectively). There was no signi cant difference regarding CMT, CFT, VDs of each segment and each sector, and super cial and deep FAZ between eyes with rst uveitis attack and those with recurrent uveitis during the attack and after recovery (p>0.05). Conclusion:The results of this study show that there is a reduction in the FAZ and an increase in the VD of the DCP of the retina during active AU, and these ndings are reversible. Acute AU may affect the macular microvasculature, which is usually temporary, especially in the DCP.

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