Background: Iron deficiency anaemia is a common tropical disease. The understanding of the different blood groups ability to retain iron in their system can give an insight into their ability to handle the disease iron deficiency anaemia.Objectives: The present study was designed to compare the level of ferritin, serum iron, total iron binding capacity (TIBC) and percentage transferrin saturation among the ABO blood groups in Enugu.
Methods:The study was prospectively conducted in 237 apparently healthy Nigerian volunteers in Enugu. Data were evaluated with SPSS (version 17) software and comparisons between groups were made using paired t-test.
Result:The results obtained showed that subjects with blood group B had lower values for ferritin (ng/mL) (83.58 ± 57.74) compared with Group A and O with ferritin (ng/mL) values of 158.80 ± 24.87 and 116.75 ± 46.34 respectively. Serum iron (µmol/L) was also lowest in the group B (20.20 ± 8.07) compared with group A and O with serum iron (µmol/L) values of 34.40 ± 15.44 and 24.00 ± 6.75 respectively. No significant differences were observed in TIBC and percentage transferrin saturation among the different blood groups.
Conclusion:Blood group B subjects showed the lowest level of serum ferritin in this work.
Aim: The aim of this study was to determine the serum/plasma levels of zinc, vitamin C and E in male subjects with type 2 diabetes mellitus to establish their concentration pattern.
Place and Duration of Study: Medical outpatient clinic, Chemical Pathology Laboratory of Enugu State University of Science and Technology Teaching Hospital, between January and December 2016.
Methodology: This prospective cohort study enrolled 40 male individuals with type 2 diabetes mellitus and 40 apparently healthy control, within the age range of 45-75 years. Zinc, vitamin C, vitamin E, and fasting blood glucose levels were determined at pre-treatment, six months and 12 months into treatment.
Results: The mean values of zinc, vitamin E and fasting blood glucose were significantly higher at pre-treatment compared to apparently healthy control values (147. 76 +/- 32.95 vs 114.31+/- 15.58 µg/dl, 11.88 +/- 3.13 vs 3.42 +/- 0.21 mg/dl and 8.08 +/- 3.22 vs 5.25+/- 0.35 mmol/l respectively) (p=<0.001, <0.001, and <0.001 respectively). At 6 month into treatment in comparison to pre-treatment values, there were significant decreases in vitamin C (3.90+/-0.97 vs 5.15+/-1.43 mg/dl) (p= 0.04). At 12 month into treatment in comparison to pre-treatment values, there were significant decreases in vitamin C (3.25+/-0.16 vs 5.15+/-1.43 mg/dl) (p= <0.001). At pre-treatment, vitamin C significantly decrease from 6.49 +/- 0.96 mg/dl in age group 45-64 years to 4.10 +/- 0.76 mg/dl in age >65 years (p=0.01).
Conclusion: The levels of vitamin C were lower at six months, but lowest at 12 month into treatment. Also vitamin C levels were found to be lower in age >65 years.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.