Glucose-6-phosphatase (G6Pase), an enzyme found mostly in the kidneys and the liver, acting significant role of supplying glucose through starvation. This study includes (84) subjects, their age ranged from (40 to 54) years. (20) subjects were healthy chosen as control group and (64) patients with type 2 diabetes mellitus were divided into three groups according to their type of anti diabetic therapy : (23) newly diagnosed group without therapy (Group1), (20) with metformin therapy (Group2) and (21) with metformin plus glibenclamide therapies( Group3). The study found that G-6-Pase activity is increased, thereby leading to an increase in endogenous glucose production (EGP) in patients with type 2 diabetes and, therefore FPG will increase. The result found that increasing G-6-Pase activity will increase the concentration of glucose in the blood and that will increase the long-term glycemic control (HbA1c%).
Hyperlipidemia case was described as a rise of lipid profile or lipoproteins in the blood. This study describe briefly investigate the reducing hyperlipideamia impact of Ginkgo biloba on the level of lipid profile.
To audit the management of diabetic septic foot [DSF] lesions in Omdurman Teaching Hospital, using Wagner classification. Patients and methods: This is a retrospective study on 208 patients with DSF admitted to Omdurman Teaching Hospital, Sudan between June 2006 and May 2007. Data were analyzed manually Results: The male to female ratio was 2:1. The mean age± SD was 56 ± 12.35 year. 16.8% patients were grade 1. 33 (15.9%) patients were grade 2. grades 3, 4, 5 patients were 66 (37 %), 38 (18.3%) and 36 (17.3%) respectively. Major lower limb amputation and mortality were 19.2%, and 6.7% respectively. Conclusion: Preventive measures for patients at risk are highly needed as well early presentation is encouraged when ulcer develops in diabetic foot to avoid subsequent complications.
This literature review focuses on drugs used for erectile dysfunction and premature ejaculation, in respect of mode of action and different analytical techniques used for their determination either alone or in combination with other drugs in different pharmaceutical and biological matrices. The cited drugs are Sildenafil, Avanafil, Apomormphine, Yohimbine, Tramadol, Dapoxetine, and Trazodone.
Parts of the Blue Nile basin showed good oil indications a decade ago, the puzzling question is why no oil draining. The common geological sense will go towards the lateral lithologic variations and its impacts on the porosity and permeability and thus towards the dynamics of the processes that governs and generate this architecture and the modes of its development. This study aims to reveal the basin architecture and its evolution, and it strongly suggests the application of constrained 2D backstripping technique using process oriented gravity modeling (POGM) technique and use the discrimination between the rift and sediment anomalies. By decompaction stratigraphic seismic sections, isostasy, recover the geometry of the crust at time of rift, calculating and adding the contribution of sediments and water to rift gravity anomaly, compare between the observed free air and the calculated gravity. POGM technique results a good discrimination between sediment and rift gravity contributions, and a value of 45 km thickness of elastic lithosphere, which is used to constrain the backstripping technique. Results from the backstripping shows the basin is a half graben type, the extension factor varies from 1.04 up to 1.1, which is accommodated by listric normal fault and the rotated blocks which compromise the hanging wall and developed to be the basin. The relative movement between these blocks and the foot wall goes different behaviors from acting independently to act as one unit this interplay change the normal faults into reverse faults, made temporal segmentation of the basin, relief, internal drainage patterns and migration of basin depocentre. From a tectonostratigraphic point of view, the Blue Nile basin evolution is given by different paleoenviroments and their positions in terms of time and space are controlled by interplay of sediment supply and basin capacity which are climatic and structural/thermal subsidence dependents respectively.
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