ABSTRACT%DFNJURXQG Obesity and periodontal diseases are two highly prevalent FKURQLF FRQGLWLRQV LQ ,QGRQHVLD %RWK REHVLW\ DQG SHULRGRQWLWLV KDYH EHHQ recognized as a major risk factor for a number of systemic diseases. Obesity related to the etiology and progression of periodontal disease was well known, but a recent study describes the role of periodontitis to obesity. 3XUSRVH The aim of this article to explain possible bidirectional relationship of periodontitis and obesity, so that dental practitioners may play an important role in management both obesity and periodontal disease. Literature review: The concept of infectobesity refers to obesity of infectious origin was accepted for the possible role of oral bacteria in the development of obesity. Excessive storage of adipose tissue in obese individuals leads to WKH UHOHDVH RI DGLSRNLQHV ZKLFK SURGXFH LQÀDPPDWRU\ 5HOHQWOHVV UHOHDVH RI SURLQÀDPPDWRU\ F\WRNLQHV LQWR WKH V\VWHPLF FLUFXODWLRQ IURP DGLSRVH tissue in obese individuals and periodontal bacteria and its product provides D V\VWHPLF LQÀDPPDWRU\ RYHUORDG DQG PD\ EH D UHVHUYRLU IRU ELGLUHFWLRQDO relationship of periodontitis and obesity. Maintaining good oral health is also fundamental for obese individuals. Dental practitioners should play important role in managements by educate their obese patients and refer the patient to physician and dietitian for a proper maintaining obesity. &RQFOXVLRQ There is a bidirectional relationship between obesity ang periodontal disease.
The development of science and technology in the field of periodontology in digital era has experienced quite rapid development. However, this development is not comparable with community's periodontal tissue health that is fairly high. Data from RISKESDAS 2018 shows the percentage of periodontitis cases in Indonesia is 74.1%. Periodontal disease is an oral disease that ranks first in the 2001 world record book record as the most common disease in humans. The high periodontal prevalence data can be due to lack of patient's knowledge of periodontal health or dental health practitioners who do not emphasize the importance of the health of periodontal tissue. The risk assessment of periodontal disease is still rarely done by dental health practitioners when compared with the assessment of the risk of dental caries. This article aims to introduce periodontal disease risk assessment methods and tools for dental health practitioners. Search for information on periodontal disease risk assessment methods and tools through PubMed with the keywords "periodontal charting" and "periodontal risk assessment". The periodontal disease risk assessment tool is chosen based on open access and free of charge. Periodontal charts and Periodontal Risk Assessment (PRA) are simple applications that can be used by all dental and oral health practitioners in explaining, evaluating and motivating patients with periodontal disorders. Periodontal chart and PRA can be used as material for evaluation and education of patient's periodontal tissue for dental health practitioners.
Background: Fibrous epulis was the most frequent non-plaque-induced gingival lesions categories from biopsied cases included hyperplastic lesions, malignancies and benign neoplasms. Because the lesion is nonspecific and histology is the foundation of a more precise diagnosis, dentists may have difficulty identifying fibrous epulis from other disorders. Furthermore, the recurrence rate is significant, thus long-term follow-up is required for fibrous epulis after therapy. Purpose: to report the therapy of fibrous epulis and the follow up after eight months. Case: A 30-year-old nonsmoker healthy man presented with a 3-month history of an enlarging mass on the anterior left mandible gingiva. A clinical diagnosis was fibrous epulis in generalized periodontitis stage III grade C. Case Management: After evaluation of initial therapy, complete excision with a surgical blade and curettage of the lesion were planned for the lesion therapy. Histopathology finding confirm the prior clinical diagnosis of fibrous epulis. Eight months following surgery, the gingiva around the region had a healthy and desirable shape with no signs of recurrence. The patient's surgical recovery was good. Conclusion: Within the limitations of this case study, complete excision and curettage of the fibrous epulis lesion are the preferred treatments because of its high recurrence rate. The histopathologic examination is crucial for determining the final diagnosis, and long-term follow-up is essential.
Objective Dental pulp stem cells (DPSCs) can be used as a component in the formation of regenerative dentine during direct pulp capping therapy. Concanavalin A (ConA) is a type of lectin with a molecular weight of 26 kDa derived from the Canavalia ensiformis plant. Lectins possess strong proliferation and differentiation abilities in various animal cells including lymphocytes, osteoblasts, and chondrocytes. The aim of study was to determine the effect of ConA on the proliferation and osteogenic differentiation of DPSCs in vitro. Materials and MethodsIn this in vitro study, DPSCs were isolated from third molars before ConA induction was performed at concentrations of 5 and 10 μg/mL. The proliferation assay was determined by 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. Osteogenic differentiation was determined by means of mineralization. Statistical Analysis Data were analyzed using analysis of variance and a Student's t-test. The p-value was set at 0.05. Results The addition of 5 and 10 µg/mL of ConA to DPSCs can significantly increase the proliferation and osteogenic differentiation of DPSCs (p ≤0.05). Conclusion ConA can increase the proliferation and osteogenic differentiation of DPSCs. AbstractKeywords ► concanavalin A ► dental pulp ► differentiation ► proliferation ► stem cell
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.