background Total Cholesterol is the amount of cholesterol carried In all cholesterol carrying particle In the blood including HDL, LDL, and VLDL. THR elderly will experience the aging process and decreased physiology function change which can lead tO reduced activity of the receptors of controlling the amount of choledterol In the body. The normal value of total cholesterol level is normal 200 mg/dl, high limit 200-239 mg/dl, and high 240 mg/dl. Risk factors can affect total cholesterol level are age gender, BMI, and blood pressure. The purpose of this study was tO determine to description of total cholesterol levels In elderly. The research method uses discritive research with purpisive sampling method involving 115 respondents take using secondary data for the elderly at Puskesmas I South Denpasar. THR results showed That most elderly respondents who experienced an increase total cholesterol were female as many as 26 people (22,6%) the age group 65-74 years as many as 18 people (15,7%), In the normal BMI category as many as 26 people (22,6%), and normal bolos pressure as many as 25 people (21,7%), high limit total cholesterol levels as many 45 people(31,9%), and high total cholesterol levels as many as 45 people (31,9%).
Background: A chemical compound is a chemical compound present in a natural source that gives it the special properties and characteristics of the plant or animal source. Snail slime is one of the traditional medicines from animals that is used by the community as a traditional medicine for healing minor wounds and toothaches. The aim of this study was to identify the active chemical compounds and antibacterial potential of snail mucus against the bacteria E. foecalis that causes periodontitis. Method: True experiment laboratory research method which is carried out by laboratory analysis of snail mucus to obtain chemical elements, the content of compounds contained in a test sample. The content of active compounds based on the Gas Chromatography-Mass Spectrometry (GCMS) test. Results: The average content of heparan sulfate with four repetitions was 16.45 mg/100g, Acharan sulfate 21.33 mg/100g, protein achasin 102.22 mg/100g, Glycoconyugat 88.6 mg/100g, Ion Ca2+ 86.2 mg/100g, Beta agglutinins 85.22 mg/100g. Toxicity test was carried out with four repetitions with concentrations of 100%, 50%, 25%, and 12.5%. And the lowest results of the toxicity test were at a concentration of 100% with a value of 0.171, while at a concentration of 50% 0.302, 25% 0.453, and 12.5% 0.768, for bacteria E. Foecalis with an inhibitory power of 23.15 mm, the category was very strong. Conclusion: The active chemical content in snail mucus is Acharan sulfate, achasin protein, Glycoconyugat, Ca2+ ion, Beta agglutinin, and the antibacterial potential of snail mucus against E. foecalis bacteria is very strong.
BACKGROUND: Bone damage is a result of periodontal disease that occurs due to changes in osteoclast and osteoblast activity in response to local inflammation. The bacteria Aggregatibacter actinomycetemcomitans produces Lipopolysaccharide (LPS), which can increase osteoclast activity. AIM: This study aimed to analyse the decrease in alveolar bone osteoclasts in periodontitis rats' model with the application of snail slime. METHODS: Wistar rats (27) with periodontitis divided into three groups, namely the control group (debridement), P1 group (debridement and application of oral snail slime) 300 Mg/Kg Body weight, P2 group (debridement, application of topical snail slime) 0.1 Mg. Osteoclast profile analysis was carried out by HE staining procedure to determine the histological feature of osteoclasts. The statistical significance was determined using the Shapiro-Wilk Test, One Way ANOVA, and Post Hoc test (p < 0.05). RESULTS: Osteoclast profile in rats with periodontitis applied with snail slime significantly decreased the number of osteoclasts with both oral and topical administration, there were significant differences in the number of osteoclasts between groups (one way ANOVA, p < 0.05) and there were no significant differences between groups P1 and P2 (Post Hoc, p > 0.05). CONCLUSION: In this study, there was a decrease in the number of osteoclasts which were slipped by snail slime in Wistar rats with periodontitis; this indicates a periodontitis healing process.
Background Anemia in pregnancy is a major health problem in developing countries with a high level of morbidity in pregnant women. The incidence of anemia in pregnancy is a condition of pregnant women with hemoglobin (Hb) levels 11 g/dL in the first and third trimesters, meanwhile in the second trimester Hb levels 10.5 g/dL. The purpose of this study was to determine the description of hemoglobin levels in pregnant women in the work area of Puskesmas Tampaksiring I. The research method used a descriptive type of research conducted in January-May 2022 with a total of 38 respondents obtained by random sampling technique. Hemoglobin levels were measured by the Point Of Care Testing (POCT) method. The results showed that 38 respondents (42.1%) had low hemoglobin levels, (55.3%) had normal hemoglobin levels, and (2.6%) had high hemoglobin levels. Low hemoglobin levels were mostly found in pregnant women who were in the range of 18-25 years, with less knowledge and were in a risky gestational age (Trimester I and III) and did not comply in taking blood-boosting tablets (TTD). The conclusion of this study is that most pregnant women have normal hemoglobin levels with a percentage of 55.3%.
Mengkudu merupakan tanaman tradisional yang dapat digunakan untuk berkumur dan mengandung antibakteri.Penelitian bertujuan untuk mengetahui efek berkumur ekstrak mengkudu dalam menghambat pertumbuhan Streptokokussp. dilaksanakan dengan metode completely randomized pre dan post test control group design. Pengambilan sampel 21orang secara simple random sampling. Bahan eksperimen menggunakan ekstrak mengkudu konsentrasi 50% dan 75%.Data hasil penelitian diuji dengan Kruskal-Wallis, Mann-Whitney dan Wilcoxon. Hasil analisis menunjukkan adaperbedaan bermakna pada pertumbuhan Streptokokus sp setelah perlakuan (p< 0,02). Berbeda bermakna pada kelompokkontrol (khlorhexidin 0,2%) dengan ekstrak mengkudu 50% dan 75% (p< 0,05), tidak berbeda bermakna antara ekstrakmengkudu 50% dengan 75% (p> 0,05). Uji analisis masing- masing kelompok sebelum dan setelah perlakuanmenunjukkan berbeda bermakna pada khlorhexidin 0,2% dengan ekstrak mengkudu 50% (p< 0,05) dan tidak berbedabermakna dengan ekstrak mengkudu 75% (p> 0,05). Kumur-kumur ekstrak mengkudu 50% dan 75% dapat menghambatpertumbuhan Streptokokus sp. penyebab dental plak, tetapi peningkatan konsentrasi dari 50% menjadi 75% tidakberpengaruh terhadap peningkatan daya hambat dari ekstrak mengkudu. Disimpulkan, kumur-kumur ekstrak mengkudu50% dan 75% dapat menghambat pertumbuhan Streptokokussp.
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