The effect of in uiuo administration of ginsenoside Rgl from Pumux ginseng on insulin binding in liver and brain membranes of mice was studied. Ginsenoside Rg, at a dose of 10mg/Lg significantly increased ['zsI]insulin binding in both tissues. The increase in insulin binding was related to an increase in the number of insulin receptors rather than to a change in the receptor affinity.
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