Kinetics of oxygen consumption, reaction product formation, and chemiluminescence during polyphenol oxidation by molecular oxygen in alkaline aqueous media with additions of L-ascorbic acid (AscH 2 ) and homocysteine (HCys) has been investigated. In these processes, AscH 2 and HCys have been shown to act as typical radical-reaction inhibitors that can be used for determinations of the radical formation rates. The rates of radical formation during oxidation of hydroquinone ( p-QH 2 ), chlorohydroquinone (Cl-QH 2 ), 2,5-dichlorohydroquinone (2,5Cl-QH 2 ), catechol (PK), 4-methylcatechol (4CH 3 -PK), pyrogallol (PG), gallic acid (GK) have been estimated.
A series of dihydroxyphenylthiazoles were synthesized via the reaction of 4-(chloroacetyl)catechol with thioamide derivatives. Their antiradical activity was studied using the reaction with the cation-radical 2,2¢-azinobis(3-ethylbenzothiazoline-6-sulfonic acid). Antimicrobial activity of the dihydroxyphenylthiazoles was studied against P. aeruginosa, C. albicans, S. epidermidis, and S. aureus. These compounds were found to belong to toxicity class 4.
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