The aim of this paper is to investigate the properties of the inhomogeneities that give rise to light scattering in polymer optical fibers (POFs). We perform several measurements in two commercial POFs of identical characteristics: these measurements, based on the side-illumination technique, consist in the detection of the total amount of scattered light guided along a POF sample under different launching conditions and in the acquisition of the corresponding near- and far-field patterns. We carry out complementary computer simulations considering inhomogeneities of different sizes at different positions inside the POF. The comparison of these simulated results with the experimental measurements will provide us with valuable information about the size and placement of the most influential inhomogeneities.

This work reports the development and application of two liquid-core microstructured polymer optical fibers (LC-mPOF) with different microstructure sizes. They are used in a fiber-enhanced Raman spectroscopy sensing platform, with the aim of detecting glucose in aqueous solutions in the clinically relevant range for sodium-glucose cotransporter 2 inhibitor therapy. The sensing platform is tested for low-concentration glucose solutions using each LC-mPOF. Results confirm that a significant enhancement of the Raman signal is achieved in comparison to conventional Raman spectroscopy. Additional measurements are carried out to obtain the valid measurement range, the resolution, and the limit of detection, showing that the LC-mPOF with 66-µm-diameter central hollow core has the highest potential for future clinical applications. Finally, preliminary tests successfully demonstrate glucose identification in urine. Index Terms-Fiber enhanced Raman spectroscopy, glucose sensing, hollow-core microstructured polymer optical fibers. I. INTRODUCTION A CCORDING to the World Health Organization, approximately 150 million people are suffering from diabetes mellitus worldwide. It is estimated that this number may well Manuscript

In this work we analyze experimentally and theoretically the properties of amplified spontaneous emission (ASE) in a rhodamine-6G-doped graded-index polymer optical fiber. A theoretical model based on the laser rate equations describes the ASE features successfully. The dependence of the ASE threshold and efficiency on fiber length is analyzed in detail.

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