The titanium implant surface was sandblasted with large grits and acid etched (SLA) to increase the implant surface for osseointegration. The topography of the titanium surface was investigated with scanning electron microscopy (SEM) and a profilometer. The SLA implant demonstrated uniform small micro pits (1-2 microm in diameter). The values of average roughness (R(a)) and maximum height (R(t)) were 1.19 microm and 10.53 microm respectively after sandblasting and the acid-etching treatment. In the cell-surface interaction study, the human osteoblast cells grew well in vitro. The in vivo evaluation of the SLA implant placed in rabbit tibia showed good bone-to-implant contact (BIC) with a mean value of 29% in total length of the implant. In the short-term clinical study, SLA implants demonstrated good clinical performance, maintaining good crestal bone height.

a b s t r a c tBackground: Amon Q2 g various dental materials and their successful restorative uses, titanium provides an excellent example of integrating science and technology involving multiple disciplines of dentistry including biomaterials, prosthodontics and surgical sciences. Titanium and its alloys have emerged as a material of choice for dental implants fulfilling all requirements biologically, chemically and mechanically. Several excellent reviews have discussed the properties of titanium and its surface characteristics that render it biocompatible. However, in most patients, titanium implants are used alongside several other metals. Presence of different metals in the same oral environment can alter the properties of titanium. Other influencing factors include intra-oral pH, salivary content, and effect of fluorides. Highlight: This review discusses the effect of the above-mentioned conditions on the properties of titanium and its alloys. An extensive literature search encompassing the properties of titanium in an altered oral environment and its interaction with other restorative materials is presented. Specific conditions that could cause titanium to corrode, specifically due to interaction with other dental materials used in oral rehabilitation, as well as methods that can be employed for passivation of titanium are discussed. Conclusion: This review presents an overview of the properties of titanium that are vital for its use in implant dentistry. From a restorative perspective, interaction between implant restoration metals, intraoral fluorides and pH may cause titanium to corrode. Therefore, in order to avoid the resulting deleterious effects, an understanding of these interactions is important for long-term prognosis of implant restorations.

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