Feline Parvovirus (FPV) had a substantial outcome on cats at various ages. This study considered being the first in Iraq focused on detection of the virus in cats with diarrhea at different age groups in some Iraqi provinces. The present study, involved a collectin of 84 fecal samples or intestinal fecal samples from an infected cats (stray and pet). These specimens were checked for detection of presence or absence the viral antigen. The checking procedure was included using the rapid antigen test kit (Anigen, Korea) and ready Polymerase Chain Reaction (PCR) kit (Santiago, Chile) to detect the virus antigen and specific genes. In addition to that, the hematological parameters had been realized. The current results show the 32 (38%) and 43 (51. 1%) were positive in rapid test and PCR, respectively. The hematological results showed 75 (89. 2%) have leukopenia.It was concluded from current study that the FPV was detected and distributed between cats of Iraq. Also, its showed that the stray cats play an important role in distribution of disease in fields.

Feline Pan Leukopenia Virus (FPV) was the more serious enteric viral infection of cats at different periods of life. Also had different generalized effects on many vital organs. The current study, aimed to investigate the essential pathological lesions which caused by the virus infection. The study which carried out on  37 infected cats at age range from 3 – 36 months,  these cats were checked previously at rapid test and PCR techniques .     The autopsy samples  were removed from infected animals and study the histopathological changes, including  bowel, heart, spleen, tongue, kidney and lung, 10 pieces of each.The results had a significant effect on the animal's life . The histopathological findings were appeared at the level of severe acute infection ,thus lastly caused death. Furthermore, the results revealed that the virus can cause different inflammatory changes at different vital organs . Key Words . Feline parvovirus, Enteritis, histopathology .