Study of Histopathological changes associated with FelinePan Leukopenia Virus infection in naturally infected cats

Abstract

Feline Pan Leukopenia Virus (FPV) was the more serious enteric viral infection of cats at different periods of life. Also had different generalized effects on many vital organs. The current study, aimed to investigate the essential pathological lesions which caused by the virus infection. The study which carried out on 37 infected cats at age range from 3 – 36 months, these cats were checked previously at rapid test and PCR techniques .
 The autopsy samples were removed from infected animals and study the histopathological changes, including bowel, heart, spleen, tongue, kidney and lung, 10 pieces of each.The results had a significant effect on the animal's life . The histopathological findings were appeared at the level of severe acute infection ,thus lastly caused death. Furthermore, the results revealed that the virus can cause different inflammatory changes at different vital organs .
 Key Words . Feline parvovirus, Enteritis, histopathology .

Molecular Diagnosis, Risk factors and Phylogenetic Analysis of Feline Panleukopenia Virus in Cats in Duhok Province, Iraq

“…There are many risk factors associated with the prevalence of the FPLV disease in cats, such as lifestyle, gender, age, breed, health status, pregnancy, vaccination status, regions, and the seasons [18,22,23]. The mortality rates of FPV in the acute stage may go up to 25-90% [24], and cause serious effects on many vital organs such as the intestine, heart, kidney, lymph nodes, spleen, lung, liver, and brain [25,26].Several laboratory techniques have been developed to detect FPV in cats, such as virus isolation and elector microscopy [27], Serological tests such as indirect ELISA, hemagglutination inhibition test, and immunofluorescence antibody test [17,20,27], and polymerase chain reaction (PCR) technique [28]. As well as the immunochromatography assay (ICA) is a quick and easy diagnostic technique that owners and veterinarians employ in clinical practice [29].…”