Flavonoids and phenolics are compounds with hydroxyl groups (-OH) bound to aromatic rings which enable them to react with reactive oxygen species and eliminate free radical activity. Single bulb garlic (Allium sativum var. solo garlic) is known to have antioxidant activity which comes from the phenolic groups. This study aims to determine the correlation of total flavonoid and phenolic levels with the antioxidant activity of ethanolic extracts from single bulb garlic grown in Magetan and Tawangmangu regions. This study included an observational analytic study with a cross-sectional design. Total flavonoid levels were measured by colorimetric method and total phenolic levels were measured by Folin-Ciocalteu method using Spectrophotometry UV-Vis. Antioxidant activity was measured by DPPH method at a wavelength of 517 nm. The data analysis used was multiple linear regression. The results showed that the extract of single bulb garlic from Magetan had total flavonoids of 12.1833 ± 0.1943 mg QE/gram, total phenolics of 70.244 mg GAE/gram, and antioxidant activity with an IC50 value of 20,216 ppm. The extract of single bulb garlic from Tawangmangu contained total flavonoids of 14.4833 ± 0.5911 mg QE/gram, total phenolics of 92.222 mg GAE/gram, and antioxidant activity with an IC50 value of 13.777 ppm. The conclusion of this study is that there is a significant correlation of total flavonoid and total phenolic content with antioxidant activity.
<span lang="EN-US">Minyak atsiri banyak digunakan sebagai bahan baku kosmetik, salah satunya minyak atsiri kulit jeruk purut sebagai antioksidan. Berkembangnya pasar minyak atsiri menjadi faktor pendorong pemalsuan karena hasil produksi rendah, tidak </span><span lang="EN-US">adanya standar kualitas minyak atsiri yang diproduksi ditandai dengan sulitnya dalam mengidentifikasi produk yang dipalsukan. Tujuan penelitian ini untuk mengetahui aktivitas antioksidan (nilai IC<sub>50</sub>) dan karakteristik minyak atsiri kulit jeruk purut sebagai acuan standar kualitas. Kulit buah jeruk purut disuling menggunakan metode penyulingan uap dan air. Aktivitas antioksidan sampel minyak atsiri kulit jeruk purut dan trolox diuji menggunakan metode CUPRAC. Persen rendemen, total minyak, kecerahan, berat jenis, indeks bias, rotasi optik, bilangan asam, kelarutan dalam alkohol, bilangan ester, dan analisis senyawa dengan GC-MS. Hasil aktivitas antioksidan minyak atsiri kulit jeruk purut dan kontrol positif trolox terdapat perbedaan signifikan (p≤0,05), dengan nilai IC<sub>50</sub> 23,4182 ppm dan 53,8605 ppm. Minyak atsiri kulit jeruk purut memiliki persen rendemen 1,86045%, tidak berwarna, berat jenis 0,84028 g/ml pada suhu 25°C, nilai indeks bias 1,4710, rotasi optik +12,70, bilangan asam 0,8415, larut dalam 1:6 bagian alkohol 90%, bilangan ester 19,635 serta mengandung 25 senyawa dengan tiga senyawa tertinggi β-pinene, limonene, sabinene. Aktivitas antioksidan minyak atsiri kulit jeruk purut tergolong sangat kuat dan karakteristik sesuai standar. </span>
Learning process evaluation of Interprofessional Education (IPE) was crucial to determine the implementation process’s success. The evaluation can be done by researching student attitudes in IPE activities. Research on students' attitudes in medical education and pharmacy study programs is expected to be a guideline for the IPE curriculum drafting team at the Faculty of Medicine, Universitas Islam Sultan Agung, Semarang, to develop future IPE learning activities. The study design was observational analytic with a cross-sectional method involving all medical and pharmacy students of the Faculty of Medicine, Universitas Islam Sultan Agung who had participated in a Small Group Discussion with TB management and met the inclusion criteria. Data collection was carried out in August 2020 using an online google form questionnaire. Data obtained through the Scale of Attitudes Toward Psychic-Pharmacist Collaboration questionnaire contains 16 questions tested for validity and reliability. Questions were answered using a 4-point Likert Scale. The statistical test analysis results on the total score of the collaboration attitude scale using the Mann Whitney Test was a p-value of 0.000. The median total score of medical and pharmacy students was 47.00 and 56.00, respectively. The p-value indicates a significant difference between the total scores of medical and pharmacy students. Based on the analysis results, the study shows significant differences in collaboration attitudes. Medical education students fall into the "moderate" category and pharmacy students in the "high" category. The pharmacy students have a more positive collaboration attitude than medical education students toward future collaborative relationships.
Indonesia merupakan negara dengan penganut agama Islam terbesar di dunia sehingga kehalalan obat di Indonesia masih menjadi isu yang menarik dan penting. Mengkonsumsi obat yang halal dan baik menjadi suatu kewajiban bagi umat Islam. Alkohol atau khamr merupakan salah satu yang diharamkan oleh Allah SWT. Majelis Ulama Indonesia (MUI) menetapkan bahwa kandungan alkohol dalam minuman tidak boleh melebihi 1%. Menurut fatwa MUI No. 40 tahun 2018, obat beralkohol masih diperbolehkan jika dalam keadaan darurat dan secara medis tidak membahayakan. Perlu untuk mengetahui kadar alkohol dalam obat agar tidak terjadi efek yang merugikan setelah penggunaan obat yang mengandung alkohol, khususnya sirup dan eliksir, sehingga diperlukan daftar obat sirup dan eliksir sebagai acuan dalam melakukan pelayanan kefarmasian. Didapatkan hasil bahwa dari produk sirup dan eliksir yang didistribusikan kepada pasien sebanyak 159 item. 150 item tidak mengandung alkohol (94%), dan 9 item mengandung alkohol (6%). Dari 9 item obat yang mengandung alkohol, 7 item mengandung alkohol di atas 1% (78%) dan 2 item mengandung alkohol di bawah 1% (22%). Hasil sosialisasi dalam upaya peningkatan pemahaman penggunaan produk eliksir dan sirup halal melalui kegiatan pengabdian di Apotek Karunia Sehat Baru Kabupaten Semarang secara statistik terdapat perbedaan pengetahuan yang bermakna antara sebelum dan setelah sosialisasi.
The prevalence of diabetes mellitus in all age groups continues to increase. One of the problems is medication adherence and blood sugar control. Compliance in drug therapy in patients with diabetes mellitus (DM) aims to control the glycemic index and other clinical outputs and prevent complications. Through educational activities, medication companion cadres (PMO) have increased their knowledge related to DM disease, drug use, and recognition and treatment of drug side effects. Apart from that, PMO families also receive Sharia-based assistance, starting from praying before taking medicine to understanding that only Allah is the healer of all diseases.
AbstrakIndonesia adalah negara dengan mayoritas penduduk beragama Islam, dengan jumlah lebih dari 87 % total penduduknya. Jumlah yang tidak kecil ini merupakan sasaran yang harus diselamatkan dari fasilitas pelayanan barang dan jasa yang merugikan dari sisi peribadatan mereka. Memberikan jaminan aman dari sisi penyedia jasa adalah langkah yang akan ditempuh oleh pusat studi Global Halal Center-UNISSULA(PS GHCU), melalui upaya penciptaan instrumen Muslim Friendly berbagai sektor jasa. Tujuan dari aktifitas yang dilakukan oleh GHCU adalah membuat instrumen yang bisa digunakan untuk mengkualifikasikan tingkat keamanan menurut nilai-nilai Islam (Muslim Friendly) dari suatu unit/lembaga yang memberikan pelayanan jasa pada konsumen/pelanggan muslim, dalam kategori pratama, utama dan paripurna. Proses penyusunan dilakukan melalui kegiatan seminar dan workshop yang mengikutkan peserta masyarakat umum, akademisi dan mahasiswa dengan narasumber dari Majelis Ulama Indonesia, Badan Penyelenggara Jaminan Produk Halal, Institute Pengkajian Halal Malaysia, dan Majelis Upaya Kesehatan Syariah Indonesia. Hasil dari aktivitas kegiatan ini adalah lima instrumen pokok dalam sektor jasa yang meliputi Muslim Friendly for Dental Clinic Rating System, Muslim Friendly for Pharmacy Rating System, Muslim Friendly for Aesthetic Clinic Rating System, Muslim Friendly for Microfinance Rating System, dan Muslim Friendly for Slaughterhouse Rating System.Kata kunci: Apotek; keuangan mikro; klinik; Muslim Friendly; pemotongan hewanAbstractIndonesia is a country with a majority of the population of Islam, with more than 87% of the total population. This population must be saved from the service facilities of goods and services that harm their worship. Providing safe guarantees from the service provider side is a step that will be taken by the Global Halal Center-UNISSULA (PS GHCU) study center, through efforts to create a "Muslim Friendly " instrument in various service sectors. The purpose of the activities carried out by GHCU is to create instruments that can be used to qualify the level of security according to Muslim Friendly values of a unit / institution that provides services to Muslim consumers / customers, in the pre-primary, primary and plenary categories. The drafting process was carried out through seminars and Workshops that included general public participants, academics and students with speakers from the Indonesian Ulema Council, Halal Product Guarantee Organizing Agency, Malaysian Halal Assessment Institute, and Indonesian Sharia Health Effort Assembly. The results of these activities are the five main instruments in the service sector which include Muslim Friendly for Dental Clinic Rating System, Muslim Friendly Pharmacy Rating System, Muslim Friendly for Aesthetic Clinic Rating System, Muslim Friendly for Microfinance Rating System, and Muslim Friendly for Slaughterhouse Rating System.Keywords: Pharmacy; microfinance; clinics; Muslim Friendly; animal slaughter
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