One in five women will experience depression over her lifetime, and one out of eight will develop breast cancer. We evaluated the effect of depression on adherence to mammography in Switzerland, where opportunistic and organized screening programs coexist. We analyzed data from 3206 women aged 50–69 who participated in the Swiss Health Survey 2012. We compared mammographic rates among women with no to mild versus moderate to severe depressive symptoms. The effect of the type of screening on the odds of undertaking a mammography was calculated using multivariable logistic regression analysis. Women with moderate to severe major depressive symptoms were more likely to have had a mammography in the previous 2 years than their nondepressed or less-depressed counterparts (51 vs. 39.2%, respectively, P = 0.005). In the multivariable analysis, women with no to mild major depression living in cantons with an organized screening program had an adjusted odds ratio of 2.7 (95% confidence interval: 2.30–3.17, P < 0.001) of having had a mammography within the past 24 months compared with those living in the regions with an opportunistic screening. The adjusted odds ratio for women with moderate to severe major depression was 4.21 (95% confidence interval: 2.13–8.33, P < 0.001). In Switzerland. adherence to mammographic screening among women with moderate to severe major depression is higher than among women with no or minimal major depressive symptoms. This increased adherence is even more pronounced in regions with organized screening.
treatment outcomes, the prevalence of histopathological types and the quality of life of patients with vulvar lesions. Methodology The case-control retrospective study involved 138 patients hospitalized in 2010-2020 at the
Solid masses of the ovaries raise the suspicion of malignancy or metastasis and require histological diagnosis. Extramedullary haematopoesis (EMH) is a rare histological finding of a mass of the adnexa. The sonographic pattern of EMH has rarely been described in the literature. Transvaginal biopsy of EMH has not been reported in the literature. We present a case of adnexal EMH in a patient affected with β-thalassaemia, and we performed a narrative review. Only in our case, the sonographic pattern was described, and a transvaginal ultrasound-guided core biopsy was used. Assessing patients’ medical history and correlating it to the findings of diagnostic imaging is of paramount importance when evaluating patients with adnexal masses. The correct interpretation of sonographic images can avoid unnecessarily invasive procedures. A transvaginal biopsy could be a safe, easy and well-tolerated method to gain definite histological diagnosis in cases where a primary ovarian malignancy is not suspected.
Objectives:To evaluate the performance of ultrasound with pattern recognition by experts, Risk of Malignancy Index (RMI) and IOTA ADNEX in the differentiation between benign and malignant adnexal masses. Methods: This is a retrospective diagnostic accuracy study, based on data prospectively collected from patients with adnexal masses (Viewpoint data base), who underwent transvaginal and/or transabdominal examination by experienced examiners in our department between December 2016 and December 2017. The risk of malignancy, defined as invasive or borderline tumours, was determined by pattern recognition and the use of two prediction models: the ADNEX model and the Risk of Malignancy Index (RMI, cut off 200). Histological findings were the clinical reference standard. Results: In the studied period, we recorded adnexal findings in 426 consecutive examinations. Of these, 122 had surgery and were included in the analysis. 60% of patients were premenopausal and 40% were postmenopausal. Seventy-seven percent of the masses were benign, 6% borderline-tumours, 16% invasive cancers. Expert pattern recognition and RMI had sensitivities of 87% and 80% at a specificity of 93% in differentiating malignant from benign tumours. The ADNEX model showed a sensitivity of 92% at a specificity of 86%. Conclusions: Although pattern recognition by experts seems to have the best discriminating power at our centre, RMI and IOTA ADNEX help in preoperative planning and are a valuable tool for triage for referral and in teaching settings.
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