Super-resolution imaging beyond Abbe's diffraction limit can be achieved by utilizing an optical medium or "metamaterial" that can either amplify or transport the decaying near-field evanescent waves that carry subwavelength features of objects. Earlier approaches at optical frequencies mostly utilized the amplification of evanescent waves in thin metallic films or metal-dielectric multilayers, but were restricted to very small thicknesses ͑Ӷ , wavelength͒ and accordingly short object-image distances, due to losses in the material. Here, we present an experimental demonstration of super-resolution imaging by a low-loss three-dimensional metamaterial nanolens consisting of aligned gold nanowires embedded in a porous alumina matrix. This composite medium possesses strongly anisotropic optical properties with negative permittivity in the nanowire axis direction, which enables the transport of both far-field and near-field components with low-loss over significant distances ͑Ͼ6 ͒, and over a broad spectral range. We demonstrate the imaging of large objects, having subwavelength features, with a resolution of at least / 4 at near-infrared wavelengths. The results are in good agreement with a theoretical model of wave propagation in anisotropic media.

No abstract

No abstract

No abstract

No abstract

Exact solutions are obtained for all the modes of wave propagation along an anisotropic cylindrical waveguide. Closed-form expressions for the energy flow on the waveguide are also derived. For extremely anisotropic waveguide where the transverse permittivity is negative (ε ⊥ < 0) while the longitudinal permittivity is positive (ε || > 0), only transverse magnetic (TM) and hybrid modes will propagate on the waveguide. At any given frequency the waveguide supports an infinite number of eigenmodes. Among the TM modes, at most only one mode is forward wave. The rest of them are backward waves which can have very large effective index. At a critical radius, the waveguide supports degenerate forward-and backward-wave modes with zero group velocity. These waveguides can be used as phase shifters and filters, and as optical buffers to slow down and trap light.

No abstract

Many studies have sought to construct a substitute to partially replace irreparably damaged meniscus. Only the meniscus allograft has been used in clinical practice as a useful substitute, and there are concerns about its longevity and inherent limitations, including availability of donor tissue and possibility of disease transmission. To overcome these limitations, we developed an acellular xenograft from whole porcine meniscus. Samples were treated with 2% Triton X-100 for 10 days and 2% sodium dodecyl sulfate for 6 days. The DNA content of extracellular matrix (ECM) scaffolds was significantly decreased compared with that of normal porcine menisci (p < 0.001). Histological analysis confirmed the maintenance of ECM integrity and anisotropic architecture in the absence of nuclei. Biochemical and biomechanical assays of the scaffolds indicated the preservation of collagen (p = 0.806), glycosaminoglycan (p = 0.188), and biomechanical properties (elastic modulus and transition stress). The scaffolds possessed good biocompatibility and supported bone marrow mesenchymal stem cells (BMSCs) proliferation for 2 weeks in vitro, with excellent region-specific recellularization in vivo. The novel scaffold has potential value for application in recellularization and transplantation strategies.