1,2-Ethenediol represents a key intermediate species in the process of sugar formation. Here, its rotational spectrum has been recorded and analyzed in order to enable its search in the interstellar medium.

The Microwave-assisted 1,3-dipolar cycloaddition of (E,E)-1,3-bisarylidenetetral-2-ones with nitrilimines affords a series of mono- and dispiropyrazolines in good to excellent yields.

Primary cycloalkylimines with a 4 to 8-membered ring have been synthesized by dehydrocyanation of the corresponding α-aminonitriles.

In memory of François DiederichKinetically unstable isocyanides as vinyl, allenyl and propargyl isocyanides react in Passerini and Ugi reactions faster than they decompose and lead to functionalized α-acyloxy amides and αamino amides, respectively, which can subsequently be used in reactions involving the unsaturated substituent.

(Z)- and (E)-iminoacetonitriles (NCCHNH), two hydrogen cyanide dimers, are described as key compounds in prebiotic chemistry. Among the many possible dimers of HCN with covalent bonds, even the second on the scale of thermodynamic stability, methylenecyanamide (CH2NCN), has been investigated little. We show that this compound can be isolated, is stable enough to give an adduct with a nucleophile or a diene, and can be easily generated under prebiotic conditions, highlighting a possible role in this medium. Comparison between isomers shows significant differences in formation and chemical reactivity.

Both theoretical and experimental study of a three-components one-pot cycloaddition reaction involving unstabilized azomethine ylides and unsymmetrical exocyclic dienones featuring a tetralone core was performed. Two new families of highly...

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