Introduction the increased prevalence of dyslipidemia in patients with type 2 diabetes mellitus (T2DM) results from uncontrolled hyperglycemia and consistently contributes to an elevated risk of cardiovascular complications. This study sought to estimate the prevalence of dyslipidemia and to investigate the relationship between glycated hemoglobin (HbA1C) and serum lipid levels in Moroccan patients with T2DM. Methods a total of 505 patients with T2DM were included in this cross-sectional study, 77.4% with chronic complications and 22.6% without. The collected data were examined using statistical package for the social sciences (SPSS) version 20.0 software and appropriate statistical methods. Results the data analysis showed that the mean and SD of age were 57.27±10.74 years. Among 505 patients with T2DM, the prevalence of hypercholesterolemia, hypertriglyceridemia, increased low-density lipoprotein cholesterol (LDL-C), and decreased HDL-C was 41.4%, 35.9%, 27.1%, and 17%, respectively. In addition, the data analysis showed that levels of total cholesterol (TC) (p≤0.001), triglycerides (p≤0.001), Low-density lipoprotein cholesterol (LDL-C) (p≤0.001), TC/HDL-C ratio (p=0.006), and LDL-C/HDL-C ratio (p=0.006) were significantly higher in T2DM patients with complications as compared to those without complications. The patients with HbA1C > 7.0% had significantly higher values of fasting blood glucose (FBG) (p≤0.001), total cholesterol (p≤0.001), triglycerides (p≤0.001), and TC/HDL-C ratio (p=0.025) as compared to the patients with HbA1C ≤ 7.0%. The HbA1C demonstrated a significant negative correlation with age (r=-0.139), and positive correlation with FBG (r=0.673), total cholesterol (r=0.189) and triglycerides (r=0.243). Conclusion our results showed that HbA1C is the most important biomarker of long-term glycemic control and can also be a good indicator of the lipid profile.

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The world is facing a pandemic due to the SARS-Coronavirus 2, since late 2019. Many questions remain unanswered regarding the disease course. Key amongst its talking point is the case of asymptomatic patients. This potentially jeopardizes infection control strategy as asymptomatic cases are difficult to identify and hence difficult to isolate. Our study intends to define the clinical and radiological features of asymptomatic COVID-19 cases, the disease course as well as highlight the role of chest CT in its management. This is a monocentric study involving 114 asymptomatic adults admitted in our COVID-19 Unit. Clinical, radiological and laboratory findings were retrospectively analyzed. Chi-squared, Fisher exact test and the student test were used for statistical analysis. Asymptomatic patients represent 51.81% of patients. There was a slight male predominance with a mean age of 37.64 years. Patients with abnormal CT had a longer hospital stay than those with unremarkable CT and even more so were older. None of the patients presented severe or critical extension of parenchymal lesions. Only two patients (4.54%) with normal CT on admission presented with abnormalities on control CT. Cases with worsening CT were older with bilateral pulmonary involvement. All patients remained asymptomatic on treatment. Even when asymptomatic, COVID-19 patients present mild lung lesions. The positivity of the initial chest CT imaging is directly correlated to the disease course. Older patients with bilateral pulmonary lesions are more likely to worsen and should be closely monitored. Moreover, it is safe to manage asymptomatic patients with normal CT in a non-hospital setting.