Introduction: The new coronavirus has caused a pandemic that has infected hundreds of millions of people around the world since its outbreak. But the cardiovascular damage caused by the new coronavirus is unknown. We have analyzed the current global scenario and the general pattern of growth. After summarizing the known relationship between cardiovascular diseases and new coronary pneumonia, relevant articles are analyzed through bibliometrics and visualization.Methods: Following our pre-designed search strategy, we selected publications on COVID-19 and cardiovascular disease in the Web of Science database. In our relevant bibliometric visualization analysis, a total of 7,028 related articles in the WOS core database up to 20th October 2022 were summarized, and the most prolific authors, the most prolific countries, and the journals and institutions that published the most articles were summarized and quantitatively analyzed.Results: SARS-CoV-2 is more infectious than SARS-CoV-1 and has significant involvement in the cardiovascular system in addition to pulmonary manifestations, with a difference of 10.16% (20.26%/10.10%) in the incidence of cardiovascular diseases. The number of cases increases in winter and decreases slightly in summer with temperature changes, but the increase in cases tends to break out of seasonality across the region as mutant strains emerge. The co-occurrence analysis found that with the progress of the epidemic, the research keywords gradually shifted from ACE2 and inflammation to the treatment of myocarditis and complications, indicating that the research on the new crown epidemic has entered the stage of prevention and treatment of complications.Conclusion: When combined with the current global pandemic trend, how to improve prognosis and reduce human body damage could become a research focus. At the same time, timely detection, prevention, and discovery of new mutant strains have also become key tasks in the fight against the epidemic, and full preparations have been made to prevent the spread of the next wave of mutant strains, and still need to continue to pay attention to the differential performance of the variant “omicron.”
Atherosclerosis is a pathological vascular state caused by the interaction of environmental and hereditary factors. Epigenetic modifications may be the bridge connecting environmental factors and genetic factors. A search for publications on the Web of Science database in the field of atherosclerosis related to epigenetics was conducted from the earliest mention to December 31, 2020. Data on total and annual publications, citations, impact factors, Hirsch (H)-index, citation times, most prolific authors, and frequently published journals were collected for quantitative and qualitative comparison. A total of 1848 publications related to epigenetics and atherosclerosis were found. The major contributing countries were the China (522, 28.23%), United States (485, 26.23%), and Germany (119, 6.44%). The greatest number of retrieved publications were published in the journal, “Arteriosclerosis, Thrombosis, and Vascular Biology” (62, 3.66%). The publication “Oxidative Stress and Diabetic Complications” was cited 2370 times. The most frequent keywords were “DNA methylation” and “LncRNA”. Publications on epigenetic research in the atherosclerosis field have increased significantly every year, indicating that the study of epigenetic modifications plays an increasingly important role in understanding the pathology of atherosclerosis.
It is widely accepted that the Japanese language is mora-timed, and the geminate obstruent, one of the three special morae in the Japanese language, forms one independent mora. Many studies have shown that perceiving Japanese geminates accurately is especially problematic for learners of Japanese. This study examines the perception of Japanese singleton and geminate contrasts by Chinese learners of Japanese (CLJ) from different dialectal backgrounds and contrasts their perception with Japanese native speakers (JNS). This study conducted two experiments. First, non-synthesized stimuli were used to test each group of participants’ perceptual sensitivity of Japanese singletons and geminates. Second, the categorical perception was accessed by adopting stimuli in which the ratio of constriction duration to entire word duration (CD/EWD) was synthesized from 15 to 60%. Results show that, although learners of Japanese had significantly lower perception levels compared to JNS regardless of their group differences (e.g., L1 background, Japanese language proficiency, etc.), they still experienced some positive transfers of L1 to achieve better perception performance. The results also suggest that CD/EWD can be considered a reliable local cue for both JNS and CLJ in categorizing Japanese singletons and geminates. In addition, the results demonstrate that variables such as medial consonant type and the learner’s Japanese proficiency affect the perception of Japanese singleton and geminate contrasts.
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