Trends and characteristics of COVID-19 and cardiovascular disease related studies

Cheng, Ao; Ren, Honghao; Ma, Zeyao; Alam, Naqash; Jia, Linying; Liu, Enqi

doi:10.3389/fphar.2023.1105459

Cited by 5 publications

(3 citation statements)

References 33 publications

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“…The countries involved in the retractions are distributed across the globe, with a total of 22 countries, of which the country most affected was China, followed by the United States, which is consistent with prior research that has identified analogous trends in other disciplines [32]; however, alternative studies have indicated that Europe surpasses all other regions in terms of retracted papers within critical medicine [17] and cardiothoracic and vascular anesthesia [33]. This disparity may be attributed to the divergent publication foundations that exist across disparate countries and disciplines [34,35].…”

Section: Discussionsupporting

confidence: 76%

Review of retracted papers in the field of neurology

Wang

Gao

Chen

et al. 2023

Euro J of Neurology

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Background and purposeDespite the growing awareness of academic fraud, its prevalence in the field of neurology has not been fully assessed. This review aims to analyze the characteristics of the retracted papers in the field of neurology and the reasons for the retraction to better understand the trends in this area and to assist to avoid retraction incidents.MethodsA total of 79 papers were included, which pertained to 22 countries and 64 journals. The marking methods for retracting original papers included watermarks (89.04%), retracted signs in the text (5.48%) and no prompt (5.48%). The median M (interquartile range [IQR]) of citations in retractions in neurology was 7 (41). Studies continued to be cited after retraction with an M (IQR) of 3 (16). The journal impact factor was between 0 and 157.335, with an M (IQR) of 5.127 (3.668). 45.21% and 31.51% papers were mainly published in the first and second quartile journals, respectively. The M (IQR) time elapsed between publication and retraction was 32 (44) months. The reasons for retraction included two major categories, academic misconduct (79.75%) and academic unintentional mistakes (20.25%).Results and conclusionsThe number of retractions in neurology has been on the rise over the past decade, with fabricated academic misconduct being the main cause of the retractions. Due to the long time lag between publication and retraction, a number of unreliable findings continue to be cited following retraction. In addition to the requisite standards of academic ethics, augmenting research training and fostering interdisciplinary collaboration are crucial in enhancing research integrity.

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Section: Discussionsupporting

confidence: 76%

Review of retracted papers in the field of neurology

Wang

Gao

Chen

et al. 2023

Euro J of Neurology

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“…Nonetheless, individuals with cardiovascular diseases, such as coronary heart disease, hypertension, and heart failure, faced elevated risks due to their underlying health conditions. While data on Omicron and cardiovascular disease outcomes continue to emerge, it remains imperative to investigate the clinical characteristics and risk factors of Omicron variants in patients with cardiovascular diseases for early identification of high-risk individuals ( 4 , 5 ). This study analyzed the clinical features and risk factors of patients with Omicron variant infections and cardiovascular diseases in Yangjiang city from December 1, 2022, to February 28, 2023, aiming to lay a groundwork for the early detection and diagnosis of at-risk patients.…”

Section: Introductionmentioning

confidence: 99%

Clinical characteristics and risk factors in patients with SARS-CoV-2 Omicron variant infection complicated with cardiovascular diseases

Yu,

Liao,

Rong

et al. 2024

Front. Med.

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ObjectiveTo investigate the clinical characteristics and risk factors of patients with SARS-CoV-2 Omicron variant infection complicated with cardiovascular diseases.MethodsA retrospective analysis of general clinical data was conducted on patients with SARS-CoV-2 omicron infection complicated with hypertension, coronary heart disease, and heart failure admitted to one hospital in Guangdong Province from December 1, 2022, to February 28, 2023. Clinical symptoms, laboratory tests, imaging examinations, treatment, and clinical outcomes were collected. Multivariate logistic regression analysis was used to analyze the risk factors for mortality in patients with SARS-CoV-2 Omicron variant infection complicated with cardiovascular diseases. ROC curves were drawn to evaluate the predictive value of CRP, D-dimer, and CK-MB in predicting the risk of death.ResultsA total of 364 confirmed cases were included, divided into the asymptomatic group, mild to moderate group, and severe to critically ill group based on the symptoms of COVID-19. There were 216 males (59.34%) and 148 females (40.66%), with a median age of 75 years. The differences between the three groups in terms of sex and age were statistically significant (p < 0.05). The top three underlying diseases were hypertension (288 cases, 79.12%), coronary heart disease (100 cases, 27.47%), and diabetes (84 cases, 23.08%). The differences in unvaccinated and triple-vaccinated patients among the three groups were statistically significant (p < 0.05). The common respiratory symptoms were cough in 237 cases (65.11%) and sputum production in 199 cases (54.67%). In terms of laboratory tests, there were statistically significant differences in neutrophils, lymphocytes, red blood cells, C-reactive protein, D-dimer, aspartate aminotransferase, and creatinine among the three groups (p < 0.05). In imaging examinations, there were statistically significant differences among the three groups in terms of unilateral pulmonary inflammation, bilateral pulmonary inflammation, and bilateral pleural effusion (p < 0.05). There were statistically significant differences among the three groups in terms of antibiotic treatment, steroid treatment, oxygen therapy, nasal cannula oxygen inhalation therapy, non-invasive ventilation, and tracheal intubation ventilation (p < 0.05). Regarding clinical outcomes, there were statistically significant differences among the three groups in terms of mortality (p < 0.05). Multivariate logistic regression analysis showed that CRP (OR = 1.012, 95% CI = 1.004–1.019) and D-dimer (OR = 1.117, 95% CI = 1.021–1.224) were independent risk factors for patient mortality. The predictive value of CRP, D-dimer, and CK-MB for the risk of death was assessed. D-dimer had the highest sensitivity (95.8%) in predicting patient mortality risk, while CRP had the highest specificity (84.4%).ConclusionFor patients with COVID-19 and concomitant cardiovascular diseases without contraindications, early administration of COVID-19 vaccines and booster shots can effectively reduce the mortality rate of severe cases. Monitoring biomarkers such as CRP, D-dimer, and CK-MB and promptly providing appropriate care can help mitigate the risk of mortality in patients.

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“…With the continuous growth of population and the aggravation of aging, the number of people suffering from cardiovascular diseases is increasing, and cardiovascular diseases have become one of the main threats to human health [1][2][3][4][5]. According to the 2023 World Health Statistics Report, in 2019, the number of deaths caused by cardiovascular diseases in the world was as high as 17.9 million, and the number of deaths is expected to continue to rise in coming years.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Plasma Treatment on the Mechanical and Biological Properties of Polyurethane Artificial Blood Vessel

Ding,

Ma,

Teng

et al. 2023

Materials

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In recent years, the incidence of cardiovascular disease has increased annually, and the demand for artificial blood vessels has been increasing. Due to the formation of thrombosis and stenosis after implantation, the application of many materials in the human body has been inhibited. Therefore, the choice of surface modification process is very important. In this paper, small-diameter polyurethane artificial blood vessels were prepared through electrospinning, and their surfaces were treated with plasma to improve their biological properties. The samples before and after plasma treatment were characterized by SEM, contact angle, XPS, and tensile testing; meanwhile, the cell compatibility and blood compatibility were evaluated. The results show that there are no significant changes to the fiber morphology or diameter distribution on the surface of the sample before and after plasma treatment. Plasma treatment can increase the proportion of oxygen-containing functional groups on the surface of the sample and improve its wettability, thereby increasing the infiltration ability of cells and promoting cell proliferation. Plasma treatment can reduce the risk of hemolysis, and does not cause platelet adhesion. Due to the etching effect of plasma, the mechanical properties of the samples decreased with the extension of plasma treatment time, which should be used as a basis to balance the mechanical property and biological property of artificial blood vessels. But on the whole, plasma treatment has positive significance for improving the comprehensive performance of samples.

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Trends and characteristics of COVID-19 and cardiovascular disease related studies

Cited by 5 publications

References 33 publications

Review of retracted papers in the field of neurology

Review of retracted papers in the field of neurology

Clinical characteristics and risk factors in patients with SARS-CoV-2 Omicron variant infection complicated with cardiovascular diseases

The Effect of Plasma Treatment on the Mechanical and Biological Properties of Polyurethane Artificial Blood Vessel

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