The catalysts generated in situ from RuCl 2 (PPh 3) 3 and α-amino substituted benzimidazole derivatives L 1 ~L 4 were used to promote the reductive amination of acetophenone to generate α-phenylethylamine, N-(1-phenylethyl) formamide and α-phenylethanol. The bulkier substituent and phenyl group on the ligand will enhance the catalytic activity. The reductive amination of acetophenone was faster at 85 ℃, while the hydrogen transfer of acetophenone to α-phenylethanol became the main reaction at 125 ℃. The hydrogen and amine resouce is the ammonium formate. The plausible mechnism was proposed.
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