Rationale
Solitary bone plasmacytoma (SBP) is a rare manifestation of plasma cell tumor. Although axial skeleton is the most frequently affected site of SBP, adjacent disc space involvement is rare. Herein we report a case of SBP in thoracic vertebra with involvement of adjacent disc space.
Patient concerns
A 57-year-old male presented with a 2-year history of intermittent back pain with activity. The patient's back pain intensity with activity was a score of 5 of the 10-point visual analog scale).
Diagnoses and intervention
The patient underwent a posterior fusion procedure from T6 to T10, and an open biopsy of the vertebral lesion confirmed that final diagnosis of SBP. The patient received postoperative radiotherapy with a total of 4000 Gy to the T7–T9 vertebral levels over a 20-day period.
Outcomes
Following radiotherapy, the patient's pain intensity was reduced to the visual analog scale score of 1 at the 6-month follow-up.
Lessons
SBP lacks typical clinical symptoms, and the accurate diagnosis before clinical intervention remains challenging. Due to the disc involvement, SBP often manifests as spinal infection. Hence, differential diagnosis in spinal lesions involving the disc should include SBP.
Background: Solitary plasmacytoma of the bone (SPB) is a rare manifestation of plasma cell tumor that usually presents as a osteolytic lesion mainly localized within the axial skeleton and the back pain is a common clinical feature.Case presentation: This case report discussed a 57-year-old male presented with low back pain caused by SBP. In this case, there is an even rarer phenomenon presented as osteolytic destruction in T7 to T9 vertebral bodies with involvement of adjacent disc spaces. This case report provided a comprehensive description of the radiographic assessment, medical management, and differential diagnosis.Conclusions: This is the first discussion focusing on differential diagnosis between spinal neoplasm and infectious diseases about SBP with involvement of adjacent disc space.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.