The joint JAXA/NASA ASTRO-H mission is the sixth in a series of highly successful X-ray missions developed by the Institute of Space and Astronautical Science (ISAS), with a planned launch in 2015. The ASTRO-H mission is equipped with a suite of sensitive instruments with the highest energy resolution ever achieved at E > 3 keV and a wide energy range spanning four decades in energy from soft X-rays to gamma-rays. The simultaneous broad band pass, coupled with the high spectral resolution of ∆E 7 eV of the micro-calorimeter, will enable a wide variety of important science themes to be pursued. ASTRO-H is expected to provide breakthrough results in scientific areas as diverse as the large-scale structure of the Universe and its evolution, the behavior of matter in the gravitational strong field regime, the physical conditions in sites of cosmic-ray acceleration, and the distribution of dark matter in galaxy clusters at different redshifts.

The Bacillus subtilis gene pgsA, which codes for the phosphatidylglycerophosphate synthase that catalyzes the committed step for the synthesis of phosphatidylglycerol (PG), is essential since Pspac-pgsA cells require IPTG for growth. Removal of the inducer caused a dramatic decrease of PG content in the membranes of cells and retarded growth. At 60 min and 120 min after removal, it was reduced to 14.1% and 8.9% of total lipid, respectively, from an initial content of 28.1%. We conjectured that the activity of some extracytoplasmic function (ECF) sigma factors, most of which are caught and regulated directly by cognate transmembrane anti-sigma factors, are affected by altered lipid composition of the membranes. Induction of the activities of ECF sigma factors (σ M and σ V ) was observed after removal of IPTG, though that of σ V was small. But other ECF sigma factors (σ W , σ X , σ Y , σ YlaC and σ Z ) and the general stress sigmas σ B and σ I were not induced. Especially σ M was activated strongly with the reduction of PG content and sustained a high level of activity, in contrast to the transient activation in PG normal cells after exposure to high salinity. This study demonstrates a new relationship between the alterations of lipid composition in the membranes and the activation of ECF sigma factors.

We observed the northern rim of the Cygnus Loop with the Suzaku observatory in 5 pointings (P21-P25). From the spatially resolved analysis, all the spectra are well fitted by the single component of the non-equilibrium ionization plasma model. From the best-fit parameters, we found that the abundances of the heavy elements are significantly lower than the solar values except those at the outermost edge in P21 and P22. The origin of the depleted metal abundances is still unclear while such deficiencies have been reported from many other rim observations of the Loop. To explain these depletion at the rim regions, we considered the several possibilities. The effects of the resonance-line-scattering and the grain condensation lower the values of the abundances. However, these are not sufficient to account for the abundance depletion observed.We found that the abundances at the outermost edge in P21 and P22 are higher than those at the other regions. From the morphological point of view, it is reasonable to consider that this abundance inhomogeneity is derived from the breakout or the thinness of the cavity wall of the Loop.

We present the analysis of Suzaku observations of the young open cluster Westerlund 2, which is filled with diffuse X-ray emission. We found that the emission consists of three thermal components or two thermal and one non-thermal components. The upper limit of the energy flux of the non-thermal component is smaller than that in the TeV band observed with H.E.S.S. This may indicate that active particle acceleration has stopped in this cluster, and that the accelerated electrons have already cooled. The gamma-ray emission observed with H.E.S.S. is likely to come from high-energy protons, which hardly cool in contrast with electrons. Metal abundances of the diffuse X-ray gas may indicate the explosion of a massive star in the past.

We report the Suzaku/XIS results of the Galactic oxygen-rich supernova remnant (SNR), G292.0+1.8, a remnant of a core-collapse supernova. The X-ray spectrum of G292.0+1.8 consists of two type plasmas, one is in collisional ionization equilibrium (CIE) and the other is in non-equilibrium ionization (NEI). The CIE plasma has nearly solar abundances, and hence would be originated from the circumstellar and interstellar mediums. The NEI plasma has super-solar abundances, and the abundance pattern indicates that the plasma originates from the supernova ejecta with a main sequence of 30-35 M ⊙ . Iron K-shell line at energy of 6.6 keV is detected for the first time in the NEI plasma.