Microcystic/Reticular Schwannoma [MRS] is a rare histological variant of Schwannoma which has been reported to mainly affect the gastrointestinal tract. Few cases involving soft tissue and various visceral and salivary glands have also been reported. However, MRS involving the spine is extremely rare with only two cases reported till date. Hereby, we present a case of Microcystic/Reticular schwannoma in a middle aged female who presented with complaints of pain and numbness in both legs. MRI findings were suggestive of an intradural extramedullary neoplasm. Diagnosis of MRS was made based on the typical histopathological features and Immunohistochemical positivity for S100. MRS is a variant of Schwannoma, which differs from the conventional Schwannoma in several aspects. Raising awareness regarding this variant is essential to the budding pathologists to prevent their misdiagnosis.
Chordomas are rare, malignant and locally aggressive tumors that are derived from the remnants of primitive notochord, out of which chondroid chordomas are even rarer. Very few case reports have described this variant, which is difficult to pick up on cytopathology alone and has a number of other differentials too. We report here a case of chondroid chordoma at the sacrococcygeal region that was diagnosed on FNAC in an elderly male patient emphasizing on its cytomorphology and how to differentiate from its cytological mimickers.
Chondroid syringoma of the skin is a rare, benign skin adnexal tumor, usually exhibited as a slowly growing intradermal or subcutaneous nodule, typically located in the head-and-neck region. Chondroid syringoma usually appears on the face; medial canthus being a rare site of predilection. The diagnosis is usually made retrospectively based on histological features of the surgically excised mass which is usually asymptomatic. We present a rare case of a 35-year-old man who presented with a painless, subcutaneous nodule in the medial canthus of the right eye. The diagnosis of chondroid syringoma was rendered. To the best of our knowledge, only one case of chondroid syringoma of the medial canthus has been documented in the literature. Histopathological examination is mandatory for arriving at the diagnosis. It should be considered in the differential diagnosis of all the slowly growing nodular lesions in the face.
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