Background: The prevalence and mortality rates of cervical cancer differ by region with the highest rates found in Latin America, Southeast Asia, and Africa. In Indonesia, cervical cancer is the second-largest contributor to the latest cases in 2020. In West Kalimantan, over 20,000 women were diagnosed with cervical cancer in 2014. This study aims to describe the characteristics of cervical cancer patients in West Kalimantan. Methods: A descriptive observational study was conducted on patients from 2017 to 2019 according to the Soedarso Hospital database. All medical records were reviewed and analyzed to obtain the variable data; they were age, ethnics, origin, stage of cervical cancer, histopathology types, and hemoglobin (Hb) level. Results: Cervical cancer patients for the 2017–2019 period totaled 147 people with 30 deaths. In this study, 97 patients from 2017 to 2019 met the inclusion criteria. Cervical cancer was found from the age of 27 years with a peak at the age of 41–60 years. Most patients came from Pontianak and Kubu Raya cities (45.4% and 14.4%, respectively) with the most ethnic groups being Malays (41.2%). A total of 43.3% of patients had a parity amount of more than five times. Most patients came at stage IIIb (45.4%). The patients present with moderate to severe anemia with the lowest Hb level of around 2.3 g/dL. Based on histopathology, the type of squamous cell carcinoma ranks the highest (70.1%). Conclusions: Cervical cancer incidence reaches the peak at adults to elderly. The amount of parity seems to contribute to the incidence of cervical cancer in West Kalimantan. Most patients came at an advanced stage and the type of squamous cell carcinoma with moderate to severe anemia
Latar Belakang: Kualitas pewarnaan preparat histologis dipengaruhi oleh proses fiksasi.. Salah satu metode fiksasi yang dapat digunakan adalah metode intravital atau perfusi. Penelitian ini bertujuan membandingkan kualitas pewarnaan preparat jaringan hepar dan testis menggunakan fiksasi metode intravital dan metode konvensional. Metode: Penelitian ini menggunakan 20 ekor tikus yang dibagi menjadi dua kelompok yaitu kelompok metode fiksasi intravital dan metode konvensional. Organ testis dan hepar dibuat preparat histologis menggunakan pewarnaan HE. Parameter yang dinilai pada setiap preparat adalah pewarnaan inti sel, sitoplasma, kejernihan pewarnaan, dan keseragaman pewarnaan. Data dianalisa menggunakan uji Fisher. Hasil: Kualitas pewarnaan jaringan testis pada metode fiksasi intravital lebih adekuat dibandingkan dengan metode konvensional dan memiliki beda bermakna (p<0,05). Kualitas pewarnaan jaringan hepar metode fiksasi intravital lebih baik dibandingkan metode konvensional, tetapi secara statistik tidak menunjukkan perbedaan antara kedua kelompok (p=0,211). Kesimpulan: Metode fiksasi formalin intravital dapat menghasilkan kualitas pewarnaan yang lebih baik pada organ testis dan hepar, meskipun kualitas pewarnaan pada hepar tidak berbeda signifikan secara statistik.
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