IntroductionAlthough the number of people receiving antiretroviral therapy (ART) in Indonesia has increased in recent years, little is known about the specific characteristics affecting adherence in this population. Indonesia is different from most of its neighbors given that it is a geographically and culturally diverse country, with a large Muslim population. We aimed to identify the current rate of adherence and explore factors that influence ART adherence.MethodsData were collected from ART-prescribed outpatients on an HIV registry at a North Jakarta hospital in 2012. Socio-demographic and behavioral characteristics were explored as factors associated with adherence using logistics regression analyses. Chi squared test was used to compare the difference between proportions. Reasons for missing medication were analyzed descriptively.ResultsTwo hundred and sixty-one patients participated, of whom 77% reported ART adherence in the last 3 months. The level of social support experienced was independently associated with adherence where some social support (p = 0.018) and good social support (p = 0.039) improved adherence compared to poor social support. Frequently cited reasons for not taking ART medication included forgetting to take medication (67%), busy with something else (63%) and asleep at medication time (60%).DiscussionThis study identified that an increase in the level of social support experienced by ART-prescribed patients was positively associated with adherence. Social support may minimize the impact of stigma among ART prescribed patients. Based on these findings, if social support is not available, alternative support through community-based organizations is recommended to maximize treatment success.
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Daun bidara arab atau yang dikenal dengan nama ilmiah Ziziphus Spina-christi L. merupakan tanaman yang telah umum digunakan pada traditional chinese medice untuk mengobati infeksi kulit hal ini dikarenakan daun bidara arab memiliki kandungan alkaloid, flavonoid dan tanin yang berfungsi sebagai antibakteri. Sampel yang digunakan dalam penelitian adalah daun bidara arab yang di ekstraksi dengan cara maserasi kemudian diuap kan dengan water bath. Ekstrak dibuat dalam tiga formula (F1, F2, F3) dengan komposisi minyak zaitun, KOH, asam stearat, CMC, SLS, nipagin, nipasol, pengaroma, aquadest serta ekstrak daun bidara arab dengan variasi konsentrasi 1%, 3%, 5%. Evaluasi yang dilakukan yaitu uji organoleptis (bentuk, bau, warna), uji pH, uji tinggi busa, uji hedonik (bentuk, aroma, warna), uji viskositas. Hasil formulasi sedian sabun cair ekstrak daun bidara arab menunjukan bahwa daun bidara arab (Ziziphus Spina-christi L.) dapat di buat sabun cair dengan memvariasikan berbagai kadar ekstrak etanol daun bidara arab (Ziziphus Spina-christi L.) serta disimpulkan bahwa formula kedua adalah formula yang terbaik.
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