Competition to ensure sustainable conditions for graduates’ knowledge, skills, and competencies (KSC) and employability for sustainable development of human resources has long been present in higher education institutions (HEIs). The purpose of this study is to examine the roles of educational processes, practical activities, and research activities as key determinants to predict KSC and employability in the context of medical education in Indonesian HEIs. Moreover, this study also reports the role of facilities in predicting educational processes, practical activities, and research activities. This survey study obtained data from 1086 respondents, who are students of two medical schools. The data were analyzed by assessing the measurement and structural model in the partial least square structural equation model (PLS-SEM). Overall, all hypotheses were supported; the strongest relationship emerged between facilities and research activities, while the lowest relationship was present between practical activities and employability. From a theoretical perspective, the findings offer a conceptual framework related to HEIs’ quality management factors. Highlighting the significant relationships, appropriate policies can be produced for more quality institutions in improving graduates’ KSC and employability for the labor market.
Objective The risk of contracting tuberculosis (TB) and the efficacy of TB therapy are affected by several factors, including genetic variation among populations. In the Indonesian population, data on the genes involved in drug transport and metabolism of TB therapy are limited. The aim of this study was to identify the genetic profile of the ABCB1 gene (rs1128503 and rs1045642) and CYP2E1 gene (rs3813867) in Indonesians with TB. This study was a cross-sectional study of 50 TB outpatients in Jambi city, Indonesia. Sociodemographic characteristics were obtained from medical records. Whole blood was collected, and genomic DNA was isolated. Single nucleotide polymorphisms were determined using polymerase chain reaction-restriction fragment length polymorphism with HaeIII, MboI, and PstI for rs1128503, rs1045642 (ABCB1), and rs3813867 (CYP2E1), respectively. Result The frequency of alleles of each gene was analyzed by Hardy–Weinberg equilibrium. The genetic profiles of ABCB1 rs1128503 and rs1045642 were varied (CC, CT, TT), while CYP2E1 rs3813867 was present in CC (wild type). The genetic variations of ABCB1 and CYP2E1 may have no significant correlation with the duration of TB therapy. Nevertheless, this study may provide as preliminary results for the genetic profiles of ABCB1 (rs1128503, rs1045642) and CYP2E1 (rs3813867) in the Indonesia population.
Background Preeclampsia is a complication during pregnancy characterised by new-onset hypertension and proteinuria that develops after 20 weeks of gestation. Dyslipidemia in pregnancy is correlated with an increased risk of preeclampsia. However, the dynamic changes in lipid metabolic product, particularly fatty acid fraction, in preeclampsia maternal circulation, are not well understood. This study aimed to investigate fatty acid fraction in preeclampsia maternal blood compared with normotensive normal pregnancy. Methods A total of 34 women who developed preeclampsia and 32 women with normotensive normal pregnancy were included in our case-control study. Maternal blood samples were collected for serum fatty acid fractions analysis and other biochemical parameters. Serum fatty acid fractions included long-chain polyunsaturated fatty acid (LCPUFA), monounsaturated fatty acid (MUFA), saturated fatty acid, and total fatty acid, measured with gas chromatography-mass spectrometry (GC-MS). The mean difference of fatty acid level was analysed using parametric and non-parametric bivariate analysis based on normality distributed data, while the risk of preeclampsia based on fatty acid fraction was analysed using a logistic regression model. Results Women with preeclampsia have lower high-density lipoprotein (53.97 ± 12.82 mg/dL vs. 63.71 ± 15.20 mg/dL, p = 0.006), higher triglyceride (284.91 ± 97.68 mg/dL vs. 232.84 ± 73.69 mg/dL, p = 0.018) than that in the normotensive group. Higher palmitoleic acid was found in women with preeclampsia compared to normotensive normal pregnancy (422.94 ± 195.99 vs. 325.71 ± 111.03 μmol/L, p = 0.037). The binary logistic regression model showed that pregnant women who had total omega-3 levels within the reference values had a higher risk of suffering preeclampsia than those with the higher reference value (odds ratio OR (95% CI): 8,5 (1.51–48.07), p = 0.015). Pregnant women who have saturated fatty acid within reference values had a lower risk for suffering preeclampsia than those in upper reference value (OR (95% CI): 0.21 (0.52–0.88), p = 0.032). Conclusion Overall, palmitoleic acid was higher in women with preeclampsia. Further analysis indicated that reference omega-3 in and high saturated fatty acid serum levels are characteristics of women with preeclampsia.
Pandemi Covid-19 telah menyebabkan kerugian yang sangat besar. Hal ini juga berdampak pada masalah-masalah psikologis yang dialami oleh masyarakat. Tujuan penelitian untuk mengetahui dampak psikologis Covid-19 pada masyarakat Jambi. Penelitian ini dilakukan dengan metode survei terbuka. Analisis dilakukan dengan kategorisasi, axial coding, persentase, dan deskripsi. Responden penelitian sebanyak 564, yang merupakan warga Jambi, terdiri dari masyarakat umum, tenaga medis, dan ibu hamil. Hasil penelitian ini menunjukkan bahwa ada beberapa dampak Covid-19 terhadap kondisi psikologis masyarakat Jambi, diantaranya; cemas, stres, takut, perasaan tertekan, dan panik. Beberapa penyebab masyarakat mengalami stres dan masalah psikologis yaitu tidak bisa beraktivitas, pembelajaran terhambat, banyaknya berita hoax, masalah ekonomi, ibadah terganggu, kebosanan, kasus positif meningkat, takut tertular Covid-19, dan tidak bisa refreshing. Selain itu, penelitian ini juga mengungkapkan persepsi terkait isolasi mandiri, kegiatan produktif di rumah, layanan kesehatan mental, tugas Psikolog dalam membantu masyarakat, dan upaya preventif yang dilakukan masyarakat Jambi secara mandiri.
Topik yang paling penting dibicarakan dalam komunitas pencinta hukum adalah kedudukan hukum sebagai sumber dari segala sumber hukum. Pertanyaan berikutnya adalah apakah secara otomatis segala produk hukum baik berbentuk peraturan perundang-undangan, kebiasaan maupun putusan pengadilan yang ada di Indonesia telah di dasarkan pada nilai-nilai yang terkandung di dalam Pancasila. Pancasila sebagai pokok-pokok pikiran dan suatu cita-cita hukum diantaranya agar supaya negara dimaksudkan dan ditujukan untuk mewujudkan kebahagiaan dan kesejahteraan, perdamaian dan kemerdekaan dalam masyarakat bangsa Indonesia. Ide dan gagasan untuk mengimplementasikan nilai-nilai yang terkandung Pancasila sebagai sumber dari segala sumber hukum di Indonesia, merupakan perintah konstitusional. Tulisan ini membahas secara lebih jauh tentang penelaahan terhadap nilai-nilai khusus yang terkandung dalam sila keempat dari Pancasila yaitu kerakyatan yang dipimpin oleh hikmah kebjaksanaan dalam permusyawaratan perwakilan, yang terdiri dari unsur-unsur karakteristik kerakyatan Indonesia, hikmat kebijaksanaan, musyawarah dan mufakat dan lembaga perwakilan.Kata Kunci : Pancasila, Demokrasi, Undang-Undang Dasar .
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