Polyvinylpyrrolidone-iodine is known as an efficient broad spectrum disinfectant with a low toxicity to living tissues. The effect of pre-operative conjunctival sac disinfection upon the corneal vitality is examined by means of endothelial photographs and pachymetry. One group of patients, who had uneventful intracapsular cataract extraction after instillation of PVP-iodine into the conjunctival sac, was compared with a control group, who underwent the same operation without PVP-iodine instillation. No corneal damage in terms of increased endothelial cell loss or corneal swelling is found in the PVP-iodine treated patients. The compound is recommended for more general ophthalmic use.
A family with vitreo-tapeto-retino-choroidal degeneration is presented. Five members of a sibship of nine and their mother are affected. Retinal changes in the form of macular degeneration and peripheral preretinal membranes are the most prominent features. Other manifestations are vitreous degeneration, optic atrophy, equatorial pigmentation, and complicated cataract. The heredity is probably autosomal dominant. Comparisons are made with the well-known hereditary vitreo-retinal degenerations, in particular with Wagner's disease. Above all, the extensive macular degeneration in two of the patients, involving the retina, the pigment epithelium, and the choriocapillaris, distinguishes the present disorder from the above-mentioned.
A material consisting of 27 patients had corneoscleral wound closure by 8-0 polyamide (supramid, nylon) sutures after intracapsular cataract extraction and intraocular lens implantation. A few months after surgery 16 patients had developed giant papillary conjunctivitis of the upper tarsus of the operated eye, associated with itching and blurring. The earlier stages of the condition, as described by other authors, could be defined in the remaining 11 patients. Cytologic testspipette samples of tear fluid and tarsal conjunctival scrapings demonstrated eosinophil leucocytes and neutrophilia in most of the giant papillary conjunctivitis cases. The conjunctival scraping proved the more sensitive test for detection of eosinophils, the pipette test being mainly an indicator of inflammatory reaction. The condition seems to be allergic with an element of mechanical irritation. The use of polyamide sutures of the 8-0 size is not recommended.
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