Background: Comorbid COVID-19 patients have worse outcomes or even death and have a longer length of stay than patients without comorbidities. The purpose of the study was to determine the relationship between comorbidities and mortality rates in COVID-19 patients at the UNS Surakarta Hospital. Methods: An analytical observational study with a cross sectional approach, conducted in January-June 2021 at UNS Sukoharjo Hospital. The subjects of this study were patients, COVID-19 who were treated at UNS Sukoharjo Hospital. Sampling was carried out by purposive sampling and obtained a sample of 132 people consisting of 66 COVID-19 patients with comorbidities and 66 COVID-19 patients without comorbidities. Data collection using medical records was then analyzed statistically using the bivariate test with Chi Square (χ²) and Mann-Whitney test. Results: Out of 132 samples, 26 samples have mortality as the outcome, with 20 patients having comorbid and 6 patients having no comorbid. Diabetes mellitus is the most frequent comorbid. To identify the effect of comorbid on mortality, chi-square test showed that the value is P=0.002. The mean value of Length of Stay in patients with comorbid is 10.18±5.94 days and without comorbid is 10.47±4.72 days. The results of the Mann Whitney test analysis obtained P value= 0.510. Conclusion: There is a significant relationship between comorbidities and mortality rates and there is no relationship between comorbidities and length of stay in COVID-19 patients at UNS Hospital Surakarta. Keywords: comorbidity, mortality rate, length of hospitalization.
Background: In the current COVID-19 pandemic, the number of hospital visits was significantly decreased. There was a decrease in the number of outpatient visits from 9911 patients in January to 5586 patients in May 2020 in UNS hospital. This study aims to know the association the level of stress, hospital service quality, and fear of COVID 19 with hospital visits at UNS Hospital. Research methods: The study was conducted at UNS Hospital in July 2020 using the questionnaire method. Research tools with hospital service quality questionnaire, stress level questionnaire, fear for COVID-19 scale. The patient group was divided into two, the on-time outpatient group, which always met the schedule visit doctor, and the loss of follow-up outpatient, which was a late schedule to the hospital. Statistical test using t-test and Mann Whitney test, p < 0,05. Results: The COVID-19 fear score (14.8 + 6.89) and the stress level (13.95 + 6.1) were higher in the out of follow-up outpatients compared to on-time outpatients. While the hospital service quality scores were quite right in all study groups and were not significantly different in the two groups (mean 21.70 + 2.08). The results showed that the lost follow-up outpatients were associated with COVID-19 fear scores (p = 0.001) and stress levels (p = 0.001), and were not related to hospital quality service levels. Conclusion: The level of stress and fear of COVID 19 decrease hospital visits at UNS Hospital.
COVID-19 increases vulnerability for populations living in regions significantly impacted by the adverse effects of climate change. There is currently no definitive treatment for COVID-19. Colchicine is a drug that can reduce the severity of COVID-19 by inhibiting the NLRP3 inflammasome. This study aims to determine the effect of colchicine administration on the high-sensitivity C-reactive protein (HsCRP) and Neutrophil to Lymphocyte Ratio (NLR) levels in COVID-19 patients. This study was conducted at the UNS Hospital in February-March 2021. The inclusion criteria were moderate-grade COVID-19 patients. HsCRP and NLR examinations were carried out before and after giving the treatment. The treatment group received 2x0.5 mg colchicine for 7 days and standard therapy, while the control group received placebo and standard therapy. Statistical test using paired t-test and independent t-test. P is significant if p is less than 0.05. The study subjects were 40 patients, with 20 patients in the control group and 20 in the treatment group. There was a decrease in NLR and HsCRP levels in the treatment group before therapy (NLR = 7.89 + 3.45; HsCRP = 5.41 + 3.24 mg/dL) compared to after therapy (NLR = 3.59 + 2.25; HsCRP = 1.41 + 1.13 mg/dL) with p = 0.001. Colchicine reduces the degree of NLR and HsCRP in COVID-19 patients.
Kejadian gawat daruat bisa terjadi pada siapa saja, kapan saja dan dimana saja. Keadaan ini menuntut kesiapan para tenaga kesehatan untuk melakukan tindakan sesuai dengan kompetensinya. Salah satu profesi kesehatan yang bertanggung jawab dalam penatalaksaan pasien gawat darurat adalah perawat. Penelitian di medan tahun 2019 menyebutkan mayoritas perawat tidak memahami cara membaca rekam jantung yang baik. Setelah berkoordinasi dengan ketua PPNI Rumah Sakit Universitas Sebelas Maret, permasalahan utama yang dialami PPNI adalah Pengetahuan mengenai cara membaca EKG pada perawat masih terbatas. Perawat tidak mengetahui gambaran rekam jantung yang berbahaya. Pelatihan membaca rekam jantung jarang ditemui di era pandemic COVID-19, dan tidak ada buku panduan khusus untuk membaca rekam jantung bagi perawat. Tahap-tahap pengabdian dilakukan dengan mengadakan workshop pelatihan membaca EKG secara daring pada minggu ketiga bulan April 2021.Tahap pengabdian selanjutnya adalah buku petunjuk EKG dan brosur EKG. Terjadi peningkatan pengetahuan perawat terhadap EKG dengan peningkatan nilai pretes 55,5 menjadi 72,5. Pelatihan EKG bagi perawat meningkatkan pengetahuan perawat sehingga meningkatkan kualitas pelayanan Kesehatan.
Backgrounds: Chronic obstructive pulmonary disease is the leading cause morbidity and mortality worldwide. Cigarette smoke and noxious agent causing oxidative stress activated nuclear factor-κB then increase inflammatory genes releases. Epigallocatechin-3-gallate green tea have antiiinflammatory effect which can be use as addition therapy for stable COPD. Methods: This study aimed to analyze the effect of EGCG to absolute neutrophil count (ANC), serum MMP-9, %FEV1, and CAT score stable COPD patients. Clinical trials of experimental with pre-test and post-test design was conducted on 30 patients in Dr. Moewardi Hospital Surakarta from February-April 2017. Samples were taken by consecutive sampling divided into treatment group (n=15) received standard therapy and green tea capsule 2x500mg/day during 28 days and control group received only standard therapy (n=15). Decreased inflammation measured by ANC and serum MMP-9, improvement of obstruction measured by %FEV1, and clinic improvement measured by CAT score. Results: There were no significant differences (P=0.135) decrease ANC treatment group (-662.45±1446.80 µL) compared control (413.79±2292.90 µL), decrease serum MMP-9 (P=0.413) treatment group (-324.34±333.56 ng/ml) compared control (-181.21±577.52 ng/ml), %FEV1 (P=0.236) treatment group (2.56±10.77), compared control (-4.30±19.12), and significant difference (P=0.034) CAT score treatment group (-1.07±1.16) compared control (-0.20±1.08). Conclusions: The addition of green tea capsule 2x500 mg/day during 28 days was significantly lowered CAT score, decreasing ANC, serum MMP-9 and increasing %FEV1 but not significant. (J Respir Indo 2018; 38(1): 7-15)
<p><strong>Pendahuluan: </strong>Prevalensi diabetes melitus (DM) secara global terus meningkat hingga menjadi 3 kali lipat pada tahun 2030. Volume kejadian yang tinggi tentu saja diikuti dengan beban biaya yang tinggi pula. Terapi DM tipe 2 saat ini hanya mencegah progresifitas DM tipe 2 dan mencegah komplikasi yang lebih parah. Salah satu inti tatalaksana DM tipe adalah edukasi ke penderita DM tipe 2 untuk menjaga kadar gula darah, bagaimana diet yang baik, dan agar rutin selalu minum obat DM. Pengabdian yang dilakukan adalah dengan mengadakan penyuluhan dan edukasi Diabetes untuk meningkatkan pengetahuan penderita DM tipe 2, membuat buku Panduan minum obat bagi penderita DM tipe 2, pemberian alat pemeriksaan gula darah, dan pemberian jarum insulin pada penderita DM tipe 2.</p><p><strong>Metode: </strong>Langkah pengabdian yang akan dilakukan meliputi pengumpulan bahan dan materi, perencanaan, dan kegiatan inti. Penyuluhan dan edukasi sebagai acara inti akan dilakukan pada tanggal 22 April 2022 dengan materi: mengenal DM tipe 2 dan gejalanya, mengenal obat-obatan DM tipe 2, olahraga dan aktifitas fisik pada DM tipe 2, komplikasi pada DM tipe 2.</p><p><strong>Hasil dan pembahasan: </strong>Evaluasi kegiatan menggunakan kuesioner kepuasan kegiatan. Semua responden menyatakan puas terhada isi materi penyuluhan.</p><p><strong>Kesimpulan: </strong>Pengabdian sudah terlaksana dengan baik, masyarakan penderita DM tipe 2 yang menjalani pelatihan mendapatkan penurunan gejala komplikasi DM tipe 2.</p>
Background: Coronavirus disease 2019 (COVID-19) has emerged as a global health catastrophe since its first reported cases in late December 2019. Critically ill COVID-19 patients have been related to cytokine storms leading to acute respiratory distress syndrome and high mortality rates. Therapeutic plasma exchange (TPE) and convalescent plasma (CP) therapy improve clinically by removing inflammatory cytokines excess and using passive antibody-containing blood, respectively. This study aimed to evaluate TPE and CP treatment for moderate-to-severe COVID-19 infection. Method: The patients were randomly divided into TPE group (n = 10), CP group (n = 11), and control group (n = 10). This 1-week quasi-experimental study with a pretest–post-test control group design was conducted in the Intensive Care Unit (ICU) of Dr. Moewardi General Hospital and Universitas Sebelas Maret (UNS) Hospital. The study comparison between groups included blood gas analysis profile (pH, base excess, PaCO2, PaO2, hematocrit, HCO3, total CO2, SaO2), FiO2, P/F ratio, COVID-19 severity, and D-dimer. The paired t-test was used to analyze every group's pretest–post-test mean difference. One-way ANOVA was performed to analyze the mean difference across the three groups. SPSS version 22.0 for Windows was used to perform statistical analyses. Result: TPE and CP groups showed significant clinical-laboratory improvement than control (p > 0.05). Furthermore, high clinical-laboratory improvement tendency was observed in CP therapy than TPE. Conclusion: The use of TPE and CP in moderate-to-severe COVID-19 patients has been related to improving clinical-laboratory outcomes.
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