Self-assembled cellulose-based hydrogels are a new type of supramolecular architecture with potential in biomedical applications. By our preparation, hydrophobic lauryl side-chains were grafted onto hydroxyethyl cellulose (HEC-C 12 ) and ibuprofen molecules were encapsulated and solubilized by poly In addition, the Korsmeyer-Peppas kinetic model gave a better correlation for the release of IBU, and the release procedure was a non-Fickian diffusion process.
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