Background:Pili have been shown to play a key role in the attachment. Results: Pilus proteins anti-SAN1518, GBS80, and GBS67 inhibited the adherence and invasion of GBS to the lung and cervical epithelial cells. Conclusion: Pilus protein contributes to the initial attachment and invasion of GBS. Significance: Pilus protein-based vaccine formulation can also be tested against GBS serotypes of India.
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