This study provides evidence that homeopathic medicines, as prescribed by experienced homeopathic practitioners, improve severity of asthma in children. Controlled studies should be conducted.
Objectives The aim of this study was to evaluate the effects of using a dietary supplement (macaroni) prepared from barley, and enriched with curcurium, ginger, onion powder and garlic powder in the management of osteoarthritis as regard the clinical assessment, changes in inflammatory and oxidative stress biomarkers. Methods Fifty one patients having bilateral grade 2-3 knee osteoarthritis were selected from the Complementary Medicine clinic at the National Research Centre; they consumed the cooked prepared macaroni daily 75 g raw for 2 months. Clinical characteristic of knee osteoarthritis, serum Interleukin 4 (IL 4), IL1β, IL6, Beta-encephalin, Malondialdehyde (MDA), Total Antioxidants Capacity (TAC), Glutathione S-Transferase Activity (GST) and ESR were detected in each patient before and after the dietary supplement consumption. Results Chemical composition of the prepared barley macaroni demonstrated that there was an increase in crude fiber, ash, protein and fat contents, and decrease in total carbohydrates content compared with control (macaroni prepared from durum wheat). 51females patients complaining of knee osteoarthritis with mean age 51 ± 8.37 years participated in the study. After 8 weeks of macaroni supplementation, most of the anthropometric measurements decreased numerical without statistical significance, while basal metabolic rate increased without significance at the end of the intervention. All clinical characteristic of knee osteoarthritis, WOMAC score, Lequesne Index and Timed Up and Go test were significantly improved at week 8. Moreover, inflammatory biomarkers were improved as achieved through elevation in serum anti- inflammatory cytokine IL4 and declining of pro-inflammatory cytokine IL1β and IL6. There was a significant reduction in ESR and elevation in serum Encephalin. In addition, dietary supplement resulted in a significant improvement in anti- oxidants status that was achieved through elevation in TAC and declining of MDA and GST Activity during follow up. Conclusions This product proved to be healthy and helpful in decreasing the intensity of knee OA associated clinical symptoms and help the patients to get their life back to near normal life. Funding Sources National Research Centre support the practical part of the work.
BACKGROUND: An overview of honey and other bee products and their health and biological health potentials was highlighted. AIM: The aim of the study was to help females alleviate their menopausal symptoms, when estrogen hormone levels decrease at the end of their fertility phase of life using natural bee products. SUBJECTS AND METHODS: Two groups of Egyptian women in the menopausal stage, suffering from different symptoms of menopause, participated as volunteers. Full clinical examination, Menopause Rating Scale, Beck anxiety score, and Beck depression score evaluations were recorded. Blood sampling and biochemical analysis were done including female sex hormones, and anti-inflammatory, and antioxidant markers. Participants consumed two tablespoon of the honey (32 ml) diluted in 250 ml of water once daily in the morning for 2 months. Control group received conventional clover honey while the other group consumed a calculated ratio of clover honey enriched with bee pollen, royal jelly, and bee gum. RESULTS: Subjects with a mean age of 49.51 ± 0.82 years who consumed enriched clover honey had significant improvement in somatic, psychological, urogenital, and anxiety score assessment and depression score evaluation. Data from this study group showed that the women experienced the disappearance of hot flushes, night sweats, generalized body pain, and psychological symptoms such as irritability, anxiety, depression, and disturbed sleeping. As for biochemical parameters, estradiol, free testosterone, the antioxidant marker malondialdehyde (MDA), and the anti-inflammatory marker interleukin-6 (IL-6) significantly improved at the end of the study. While the control group had mean age of 48.24 ± 0.74 years, they experienced significant improvement of the somatic subscale, depression score, and MDA, and there was no significant effect on urogenital symptoms, anxiety score, IL-6, or any of the female sex hormones. CONCLUSION: Adding Bee pollen, propolis, and royal jelly to the clover honey are more effective in slowing down menopausal symptoms.
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