Abstract:As of May 2014, the Directory of Open Access Journals (DOAJ) listed close to ten thousand fully open access, peer reviewed, scholarly journals. Most of these journals do not charge article processing charges (APCs). This article reports the results of a survey of the 2567 journals, or 26% of journals listed in DOAJ, that do have APCs based on a sample of 1432 of these journals. Results indicate a volatile sector that would make future APCs difficult to predict for budgeting purposes. DOAJ and publisher title lists often did not closely match. A number of journals were found on examination not to have APCs. A wide range of publication costs was found for every publisher type. The average (mean) APC of $964 contrasts with a mode of $0. At least 61% of publishers using APCs are commercial in nature, while many publishers are of unknown types. The vast majority of journals charging APCs (80%) were found to offer one or more variations on pricing, such as discounts for authors from mid to low income countries, differential pricing based on article type, institutional or society membership, and/or optional charges for extras such as English language editing services or fast track of articles. The complexity and volatility of this publishing landscape is discussed.
Overall, good agreement was found between ACE and MC dose calculations for a single I-125 seed and in front of the COMS plaques in water. More complex scenarios need to be investigated to determine how well ACE handles heterogeneous patient materials.
Academic library budgets are the primary source of revenue for scholarly journal publishing. There is more than enough money in the budgets of academic libraries to fund a fully open access scholarly journal publishing system. Seeking efficiencies, such as a reasonable average cost per article, will be key to a successful transition. This article presents macro level economic data and analysis illustrating the key factors and potential for cost savings.
Patients with heart failure (HF) who have been discharged from a home care agency are a particularly vulnerable group at risk for poor outcomes and high rehositalization rates. The primary aim of this experimental study was to determine the efficacy of a telemonitoring and self-care education intervention in reducing hospitalization and improving quality of life and patient's knowledge of HF after home care discharge. Ninety-three participants completed the study. The primary outcome of 90-day post-home care discharge hospitalization was significantly reduced in the intervention group compared to controls (9 vs. 18, p -.046). HF knowledge (p = .013) and QOL (p = .004) were significantly increased in intervention group patients in comparison to control group patients' at the study endpoint.
Ionizing radiation (IR) is environmentally prevalent and, depending on dose and linear energy transfer (LET), can elicit serious health effects by damaging DNA. Relative to low LET photon radiation (X-rays, gamma rays), higher LET particle radiation produces more disease causing, complex DNA damage that is substantially more challenging to resolve quickly or accurately. Despite the majority of human lifetime IR exposure involving long-term, repetitive, low doses of high LET alpha particles (e.g. radon gas inhalation), technological limitations to deliver alpha particles in the laboratory conveniently, repeatedly, over a prolonged period, in low doses and in an affordable, high-throughput manner have constrained DNA damage and repair research on this topic. To resolve this, we developed an inexpensive, high capacity, 96-well plate-compatible alpha particle irradiator capable of delivering adjustable, low mGy/s particle radiation doses in multiple model systems and on the benchtop of a standard laboratory. The system enables monitoring alpha particle effects on DNA damage repair and signalling, genome stability pathways, oxidative stress, cell cycle phase distribution, cell viability and clonogenic survival using numerous microscopy-based and physical techniques. Most importantly, this method is foundational for high-throughput genetic screening and small molecule testing in mammalian and yeast cells.
A modified procedure for performing EBT3 film calibration was established for use with low-energy brachytherapy seeds and high dose exposures. The energy dependence between 6 MV and I-125 photons is significant such that film calibrations should be done with an appropriately low-energy source when performing low-energy brachytherapy dose measurements. Two-segment piecewise fitting with the inclusion of errors in measured optical density as well as dose was found to result in the most accurate calibration curves. Above doses of 1 Gy, absolute dose measurements can be made with an accuracy of 1.6% for 6 MV beams and 5.7% for I-125 seed exposures if using the I-125 source for calibration, or 2.3% if using the 75 kVp photon beam for calibration.
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