Dengue fever is a debilitating and infectious disease that could be life-threatening. It is caused by the dengue virus which affects millions of people in the tropical area. Currently, there is no cure for the disease as there is no vaccine available. Thus, prevention of the vector population using conventional methods is by far the main strategy but has been found ineffective. A genetically modified (GM) mosquito is among the favoured alternatives to curb dengue fever in Malaysia. Past studies have shown that development and diffusion of gene technology products depends heavily upon public acceptance. The purpose of this study is to identify the relevant factors influencing stakeholders' attitudes toward the GM Aedes mosquito and to analyse the relationships between all the factors using the structural equation model. A survey was carried out on 509 respondents from various stakeholder groups in the Klang Valley region of Malaysia. Results of the survey have confirmed that public perception towards complex issues such as gene technology should be seen as a multi-faceted process. The perceived benefit-perceived risk balance is very important in determining the most predominant predictor of attitudes toward a GM mosquito. In this study the stakeholders perceived the benefit of the GM mosquito as outweighing its risk, translating perceived benefit as the most important direct predictor of attitudes toward the GM mosquito. Trust in key players has a direct influence on attitudes toward the GM mosquito while moral concern exhibited an indirect influence through perceived benefits. Other factors such as attitudes toward technology and nature were also indirect predictors of attitudes toward the GM mosquito while religiosity and engagement did not exhibited any significant roles. The research findings serve as a useful database to understand public acceptance and the social construct of public attitudes towards the GM mosquito to combat dengue.

The Malaysian stakeholders were cautious about xenotransplantation. This study showed that their views regarding the application are complex and multifaceted.

BackgroundConcern about the inevitable depletion of global energy resources is rising and many countries are shifting their focus to renewable energy. Biodiesel is one promising energy source that has garnered much public attention in recent years. Many believe that this alternative source of energy will be able to sustain the need for increased energy security while at the same time being friendly to the environment. Public opinion, as well as proactive measures by key players in industry, may play a decisive role in steering the direction of biodiesel development throughout the world. Past studies have suggested that public acceptance of biofuels could be shaped by critical consideration of the risk–benefit perceptions of the product, in addition to the impact on the economy and environment.ResultsThe purpose of this study was to identify the relevant factors influencing stakeholders’ attitudes towards biodiesel derived from crops such as palm oil for vehicle use, as well as to analyse the interrelationships of these factors in an attitude model. A survey of 509 respondents, consisting of various stakeholder groups in the Klang Valley region of Malaysia, was undertaken. The results of the study have substantiated the premise that the most important direct predictor of attitude to biodiesel is the perceived benefits (β = 0.80, p < 0.001). Attitude towards biodiesel also involves the interplay between other factors, such as engagement to biotechnology, trust of key players, attitude to technology, and perceived risk.ConclusionAlthough perceived benefit has emerged as the main predictor of public support of biodiesel, the existence of other significant interactions among variables leads to the conclusion that public attitude towards biodiesel should be seen as a multi-faceted process and should be strongly considered prior to its commercialisation.

The Malaysian Cabinet's approval of MyCohort in 2005 was seen as the crucial step toward the country having its very first biobank to improve the prevention, diagnosis and treatment of diseases. Past studies have shown that public attitudes towards biobanking depend heavily upon several factors including public engagement with biobanks, trust in key actors, privacy and data security, perceived benefit, altruism and certain demographic variables. The objective of this paper is to assess and compare the attitude levels of the Malaysian stakeholders' towards the application of biobanks across education levels and religion. A survey was carried out on 509 adult respondents in the Klang Valley region of Malaysia. Results of the study have substantiated that the Malaysian stakeholders' attitudes towards biobank were classified as high. Despite their high levels of perceived benefit and religious acceptance, they also expressed moderately high levels of concern when it comes to issues of data and specimen protection; this suggests that the Malaysian stakeholders also tend to be critical upon expressing their views towards a complex system such as biobanks. One-way MANOVA initially has detected a significant difference of attitude towards biobanks across stakeholder groups, education level and religion. Series of univariate analysis following the MANOVA, as well as Post Hoc analysis, also confirm significant difference of attitude existing across stakeholders; however, no significant differences were detected across education level and religion. The research finding serves as a useful benchmark for scientists and government regulators to understand public attitudes to biobanks before they are set into use.

BackgroundThe demand in biobanking for the collection and maintenance of biological specimens and personal data from civilians to improve the prevention, diagnosis and treatment of diseases has increased notably. Despite the advancement, certain issues, specifically those related to privacy and data protection, have been critically discussed. The purposes of this study are to assess the willingness of stakeholders to participate in biobanking and to determine its predictors.MethodsA survey of 469 respondents from various stakeholder groups in the Klang Valley region of Malaysia was carried out. Based on previous research, a multi-dimensional instrument measuring willingness to participate in biobanking, and its predictors, was constructed and validated. A single step Structural Equation Modelling was performed to analyse the measurements and structural model using the International Business Machines Corporation Software Package for Social Sciences, Analysis of Moment Structures (IBM SPSS Amos) version 20 with a maximum likelihood function.ResultsMalaysian stakeholders in the Klang Valley were found to be cautious of biobanks. Although they perceived the biobanks as moderately beneficial (mean score of 4.65) and were moderately willing to participate in biobanking (mean score of 4.10), they professed moderate concern about data and specimen protection issues (mean score of 4.33). Willingness to participate in biobanking was predominantly determined by four direct predictors: specific application-linked perceptions of their benefits (β = 0.35, p < 0.001), issues of data and specimen protection (β = − 0.31, p < 0.001) and religious acceptance (β = 0.15, p < 0.05) and trust in key players (β = 0.20, p < 0.001). The stakeholders’ willingness to participate in biobanking also involves the intricate relationships between the above-mentioned factors and other predictors, such as attitudes regarding technology, religiosity and engagement.ConclusionsThe findings of this study reaffirmed that stakeholders’ willingness to participate in biobanking is a complex phenomenon that should be viewed from a multidimensional perspective. Stakeholder willingness to participate in biobanking is warranted when direct predictors (benefits, issues of data and specimen protection, religious acceptance, and trust in key players) as well as indirect factors are well accounted for.Electronic supplementary materialThe online version of this article (10.1186/s12874-018-0619-2) contains supplementary material, which is available to authorized users.