clinicaltrials.gov Identifier: NCT00198822.
Objective To describe proportionate mortality and causes of death unrelated to pregnancy.Design Prospective cohort study.Setting Rural northwest Bangladesh.Population A cohort of 133 617 married women of reproductive age.Methods Verbal autopsies were conducted for women who died whilst under surveillance in the cohort trial. Physician-assigned causes of death based on verbal autopsies were used to categorise deaths.Main outcome measures The proportion of deaths due to non-communicable diseases, infectious diseases, injury or pregnancy.Results Of the 1107 deaths occurring among women between 2001 and 2007, 48% were attributed to non-communicable diseases, 22% to pregnancy, 17% to infections, 9% to injury and 4% to other causes.Conclusions Although focus on pregnancy-related mortality remains important, more attention is warranted on non-communicable diseases among women of reproductive age.
Introduction:Preterm labour is defined as the presence of uterine contractions of sufficient frequency and intensity to effect progressive effacement and dilatation prior to term gestation. Preterm labour and preterm births occur in approximately 12 % of all pregnancies and is the leading cause of neonatal death in the United States as well in the developing countries 1 . In addition, preterm birth accounts for 70% of neonatal morbidity, and mortality, and health care spent on the neonate 2 .Despite the current use of material, effort and money in perinatal medical technology neonatal mortality rates continue to remain high. Implementation of effective risk identification, strategies and programms for the prevention of preterm labour may lead to successful reduction of perinatal morbidity and mortality associated with prematurity. This in turn requires both an improved understanding of the psychosocial risk factors, etiology, mechanisms of preterm labour, and programmes for accurate identification of pregnant women at risk of premature labour and delivery 3 .Until an etiological treatment is found for preterm labour, treatment is based on preventing unwanted uterine contractions. Several therapeutic attempts have been made to inhibit uterine activity such as ethanol, prostaglandin synthetase inhibitors, magnesium sulphate, ritordine and beta-sympathomimetics. The side effects as well as the limited success have stimulated the investigators to search for new drugs such as oxytocin antagonists, calcium channel openers and calcium channel blockers 4 .Nifedipine, a calcium channel blocking agent inhibits smooth muscle contraction by impeding the flow of calcium across the muscle cell membrane.The aim of the study was to evaluate the tocolytic efficacy of nifedipine in preventing preterm labour and to evaluate the side effects. Material and MethodsThe study was conducted in the Institute of Child & Mother Health Matuail Dhaka & a private hospital, between January 2005 till December 2008. Eighty nine patients presenting with preterm labour between 30-34 weeks with singleton pregnancy and intact membrane were included in the study. Preterm labour was diagnosed by minimum of four contractions in 30 min. and cervical dilatation less than 3 cm. The subjects who met the inclusion criteria were randomized to receive either oral nifedipine or placebo by lottery method. There were 45 patients in the nifedipine group and 44 in the placebo group. Written consent was obtained from them. Women were considered to enroll for the study if preterm labour occurred between 30 and 34 weeks of singleton pregnancy and intact membrane. Exclusion criteria A Prospective Randomised Trial of Nifedipine Versus Placebo in Preterm Labour
This prospective study was conducted to determine the effect of Infrared Radiation on the patients presented with Bell’s palsy attended at the Department of Physical Medicine and Rehabilitation, Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh from January 2012 to June 2012. By dividing in equal two groups ‘A’ and ‘B’ (30 patients in each group) a total of sixty (60) patients with Bell’s palsy were included in this study according to the selection criteria. Group- A patients were received Infrared Radiation (IRR) including Proprioceptive Neuromuscular Fascilitation (PNF) exercise, Drugs (Prednisolone & Acyclovir) and Counseling for their recovery, where Group- B didn’t receive IRR but received rest of management. In Group- A, 25(83.33%) patients recovered completely and among them 12 (40%) patients recovered early (within 2 months). In Group- B, 23(76.67%) patients recovered completely, among them 7 (23.33%) patient recovered early. The difference was statistically significant. The outcome of early recovery is better with the patients treated with combined effect of IRR, PNF exercise and drugs compared with combined effect of PNF, exercise & drugs. The patients who attended with facial nerve paralysis House-Brackmann (HB) Grade IV to VI during initial presentation have reduced chance of full recovery of facial nerve paralysis.Bangladesh Med J. 2017 Jan; 46 (1): 1-6
This randomized controlled trial was conducted in Department of Physical Medicine and Rehabilitation of Bangabandhu Sheikh Mujib Medical University, Dhaka during the period from March 2014 to August 2014 to evaluate the effect of ultrasound therapy (UST) on patients of carpal tunnel syndrome. Total 110 subjects were participated in this study and they were selected randomly divided in two groups by lottery. Group-A was treated with UST, Exercise, Wrist splint, non steroidal anti inflammatory drugs (NSAIDs) and group-B received Exercise, Wrist splint and NSAIDs. Treatment continued for a period of 6 weeks. Group-A were compared to group B by both Visual Analog Scale (VAS) and Levine Symptom severity scale(LSSS) after 3 weeks and 6weeks of treatment. The result showed mean VAS at pretreatment (W0) in group-A was 6.42 ±1.23 and in group-B was 6.17±0.74. Group-A was 1.82±0.43 and in group-B was 3.1±0.23 in their follow up after 3 weeks (W 3) In Group-A was 1.71(±0.52) and in group-B was 2.52(±0.49) at 2nd follow up (W6) after 6 weeks. Mean LSSSat pretreatment (W0),1st follow up after 3 weeks (W 3), 2nd follow up (W 6) after 6 weeksin group-A was 31.64±1.55, 14.32 ± 2.29 and 14.31 ±1.12 respectively,and in group-B was 31.3±0.74,18.51±0.92and 18.31 ± 0.42 respectively.This study revealed that continuous mode of US therapy with exercise, wrist splint, NSAIDs have better outcome in case of Carpal tunnel syndrome patients. J Shaheed Suhrawardy Med Coll, June 2019, Vol.11(1); 24-27
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