We have hypothesized that the Oxidative Stress Index (OSI) can be used to predict the severity of COVID-19. The recently published Clinical Risk Score Calculation (CRSC), based upon clinical data ascertained at the time of hospital admission for patients in 575 hospitals in China following the COVID-19 outbreak, confirms and validates our hypothesis.
Severity of the COVID-19 disease ranges from imperceptible to death with the aged and those with pre-existing conditions being particularly vulnerable to severe symptoms. Other factors have also been shown to influence COVID-19 severity. These include smoking, vaping and exposure to air pollution. These factors have a one thing in common, all raise oxidative stress. The Oxidative Stress Index, derived from a questionnaire and reflective of oxidative stress level, is proposed as a non-invasive way to predict the severity of COVID-19 in those impacted by the Coronavirus.
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