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Hemoglobin I was recently found in a Negro family. The amino acid substitution was shown to occur in the sixteenth residue of the α chain (lys → asp) and to be identical with hemoglobin I described by Murayama.10 The minor component, I2, was demonstrated by agar gel electrophoresis.

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The relation between physiological factors and personal and intellectual factors is a subject about which much is surmised and little is known. To what extent does the mind depend on the body? This paper describes an experiment which attempts to throw some new light on this question which has been asked since time immemorial.