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ObjectivesThe relationship between elevated internal aluminum loads and central nervous system function was studied among aluminum welders, and the threshold level for adverse effect was defined.Methods For 65 aluminum welders and 25 current mild steel welders body burden was estimated, and the aluminum concentrations in serum (S-Al) and urine (U-A1) were analyzed with graphite furnace atomic absorption spectrometry with Zeeman background correction. Referents and low-exposure and high-exposure groups were defined according to an aggregated measure of aluminum body burden, the group median S-A1 levels being 0.08, 0.14, and 0.46 pmolll, respectively, and the corresponding values for U-A1 being 0.4, 1.8, and 7.1 pmolll. Central nervous system functions were assessed with a neuropsychological test battery, symptom and mood questionnaires, a visual and quantitative analysis of electroencephalography (EEG), and P3 event-related potentials with pitch and duration paradigms.Results Subjective symptoms showed exposure-related increases in fatigue, mild depression, and memory and concentration problems. Neuropsychological testing revealed a circumscribed effect of aluminum, mainly in tasks demanding complex attention and the processing of information in the working memory system and in the analysis and recall of abstract visual patterns. The visual EEG analysis revealed pathological findings only for aluminum welders. Mild, diffuse abnormalities were found in 17% of the low-exposure group and 27% of the high-exposure group, and mild to moderate epileptiform abnormalities at a frequency of 7% and 17%, respectively. C O~C~U S~O~S Both objective neurophysiological and neuropsychological measures and subjective symptomatology indicated mild but unequivocal findings dose-dependently associated with increased aluminum body burden. The study indicates that the body burden threshold for adverse effect approximates an U-A1 value of 4-6 pmol/l and an S-A1 value of 0.25-0.35 kmol/l among aluminum welders.

The purpose of the study was to assess the working conditions in hairdressing salons and the influence of work factors on the workers' health. Twenty randomly sampled hairdressing salons in the Helsinki, Finland, metropolitan area were selected for the study. The study was performed during winter 1994-1995; it included a survey of the hairdressing chemicals in use, the measurement of physical and chemical working conditions, and a self-administered questionnaire of the work environment and health of the workers. The air temperature varied between 16-25 degrees C, air velocity 0.02-0.3 m/s, and relative humidity, 18-42 percent. The total dust concentration varied between 66-133 micrograms/m3. The concentration of volatile organic compounds was 84-465 micrograms/m3 and the peaks rose to 25-45 mg/m3. The highest concentration of ammonia detected was 3.5 mg/m3. The long-term concentrations of thioglycolates and persulfates were at their lowest below the detection limit, and at their highest 1.8 micrograms/m3 for thioglycolates and 4.7 micrograms/m3 for persulfates, respectively, and the peaks of persulfates, 30 micrograms/m3. Hairdressing chemicals, awkward work postures, and repetitive movements were the most frequent causes of discomfort and for some had caused a work-related disease. Good general ventilation decreased the health complaints caused by hairdressing chemicals, but caused discomfort as a result of drafts. On average, the physical and chemical working conditions in the hairdressing salons were satisfactory compared with the Finnish criterion for indoor climate. However, the frequent high peak concentrations of chemicals during dyeing, bleaching, permanenting, and aerosol spraying still pose a significant health problem. Although effective general ventilation alleviated the effects of the air pollutants, it could not completely solve the problem. Therefore, local exhaust ventilation is recommended at the mixing places for hairdressing chemicals and wherever they are applied to the hair. According to our results, already increasing the air exchange rate up to 5 to 7 times per hour during the high exposure jobs would improve the situation.

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Hairdressers suffering from atopic diseases, hand eczema, and strain injuries of the elbow and wrist are at higher risk of leaving the profession. Active modes of intervention are needed to maintain their working ability. The tools available in the occupational health service are: information on hazards, optimization of working conditions, personal protection, and timely medical care and rehabilitation.

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We conducted a retrospective cohort study to investigate whether work as a cabin attendant is related to an increased risk for spontaneous abortion. Data on female cabin crew members were linked to medical records on pregnancies. There were 1751 eligible pregnancies for the final analysis. Flight attendants who worked during early pregnancy had a slightly elevated risk of spontaneous abortion, as compared with attendants who were pregnant outside a time span of active flying (odds ratio [OR] = 1.3; 95% confidence interval [CI], 0.9 to 1.8). During the earliest years of the study period (1973 through 1977), the risk seemed to be decreased (OR = 0.4; 95% CI, 0.2 to 1.1), whereas during the later years (1978 through 1994) the risk was increased (OR = 1.6; 95% CI, 1.1 to 2.4). The results are in agreement with earlier studies, showing suggestive evidence of a slightly increased risk of spontaneous abortion among female cabin crew members.