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Oral submucous fibrosis is commonly seen in the adult population of the ethnic minorities in the UK, although its presentation in a child is rare. Whilst the condition is considered multifactorial and irreversible, we present a case of oral submucous fibrosis in a 12-year-old Bangladeshi boy whose cessation of habitual betel nut chewing and forcible mouth chewing exercises led to an improvement in his mouth opening, although his ability to protrude his tongue remained unaltered. The clinical features, pathogenesis and management of submucous fibrosis are described. The widespread use of betel quid among Asians in the UK is summarized and the importance of its recognition as a precancerous condition is emphasized.

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immunoglobulin G (IgG) using the Automation ELISA IgG Kit manufactured by Automation INC. U S A . D a t a o b t a i n e d w e r e summarized using percentages and frequency tables. Results were analyzed using Epi-info version 3.0.Three hundred and fifty three pupils were recruited for the study. The overall prevalence rate for VZV infection was 66.3% with the value in males being 68.5% and in females 63.9%. The prevalence of VZV infection increased with age in both sexes. A high percentage of children (60%) were seropositive at 4-6 years.The study shows a 66.3% prevalence of VZV infection among children in Kaduna State. T h i s h i g h p r e v a l e n c e r a t e necessitates further studies to establish the burden of the problem in Nigeria and rationalize the institution of preventive measures against the infection, particularly i m m u n o c o m p r o m i s e d y o u n g children. Results: Conclusion:Received

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We report a 17-month-old boy who was a known case of Lesch-Nyhan syndrome and presented with self-inflicted oral ulcerations of his lips and cheeks. He had a normal complement of caries-free deciduous teeth. Initially a conservative approach was planned and a bite plate made, but as a result of poor compliance and persistent ulceration and after consultation with his parents it was decided to extract all deciduous teeth. Introductionpurine metabolism. HPRT catalyses the condensation

Despite of the invasive procedure that might cause postoperative effect, OSCC patients in the current study showed a better quality of life after cancer removal.