Aim; To compare the impact of the orthodontics-first approach (OFA) with the surgeryfirst approach (SFA), for the correction of dentofacial deformities, on quality of life, anxiety and depression. Materials and methods; Data were collected from 32 patients (aged 17-47 years), all treated through a single multidisciplinary orthognathic clinic. Patients completed a 22-item Orthognathic Quality of Life Questionnaire (OQLQ), a 7-item Generalized Anxiety Disorder (GAD-7) questionnaire and a 9-item Patient Health Questionnaire (PHQ-9), at one week preoperatively (T1), then 6 weeks (T2) and 6 months (T3) postoperatively. Results; the quality of life was statistically higher for the SFA group preoperatively (P = 0.010, ES = 0.96). The mean score and the individual domain scores, of the OQLQ, showed significant improvements at 6 weeks and 6 months postoperatively. The facial aesthetic domain showed the largest improvement (ES = 2.5 in OFA and ES = 2.2 in SFA). Patients in the OFA group experienced a lower quality of life and greater deterioration in social life immediately prior to surgery. The anxiety and depression scores did not significantly reduce postoperatively in either group. The assumption that all psychological aspects of the patient's life improve following orthognathic surgery is not supported by the results of this study. Conclusion; SFA eliminates the deterioration in social life which is associated with the presurgical orthodontic decompensation phase. results suggest that the Manuscript with title (excluding any author details including names and affiliations) Click here to view linked References
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