The results of our study show that high expression of HOXA13 is associated with the progression of bladder cancer and that HOXA13 might serve as a biomarker for prognosis of bladder cancer.
remain unknown. This study aimed to analyze possible risk factors that are associated with the neoplastic transformation of gastric hyperplastic polyps. Results Demographics features. During January 2010 and June 2017, there were 6418 cases of gastric polyp diagnosed. 1115 of these (17.4%, 1115/6418) were histologically confirmed GHPs. 30 of these GHPs (2.69%, 30/1115) were diagnosed as containing dysplasia or adenocarcinoma. The mean age was 61.73 ± 9.024 years old (range 32-79). Absence of Helicobacter pylori was found in 63.6% (35/55). Within the 16 patients who showed evidence of neoplastic transformation there were 12 females and 4 males, the mean age was 63.44 ± 12.27 years (range 32-79). 9 (56.3%) of the patients who had GHPs with neoplastic transformation and 10 (25.6%) of the patients with pure GHPs had a history of anaemia. The patients who had a history of anaemia were more likely to have GHPs with evidence of neoplastic transformation (9/16 vs 10/39 in the GHP patients with or without neoplastic transformation, χ 2 = 4.701, P = 0.030) (Table 1). The initial indications for performing EGD were: 27 patients screening for early gastric cancer, 15 bloating, 4 abdominal pain, 7 heartburn or acid reflux and 2 anaemia. However, 20 patients (36.4%) actually had evidence of anaemia when tested. Only 3 patients took PPI, but all of them had normal fasting serum gastrin-17 concentrations.
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