Objective: To determine the frequency of thrombocytopenia in pre-eclamptic women presented at Isra University Hospital Hyderabad. Patients and Methods: This cross sectional descriptive study of six months study was conducted at Isra university hospital from April 2019 to September 2019. All the patients between ≥18 - 45 years of age diagnosed preeclampsia were admitted and evaluated for thrombocytopenia. Results: During six month study period, total of 177 patients with preeclampsia were evaluated for thrombocytopenia. The majority of patients were from urban areas 125/177 (70.6%). The mean ±SD for maternal and gestational age of the preeclamptic patient was 32.75±8.85 and 28.75±7.63 whereas the mean platelet count was 93200±10.74 respectively. The majority of the patients were 21-30 years of age (54.8%) and the finding was statistically significant with gestational age [p=0.002]. The thrombocytopenia was observed in 99/177 (55.9%) and is statistically with relation to maternal age, gestational age and parity while in context to gravida and duration of disease it is non significant. Conclusion: A significantly high frequency of thrombocytopenia (55.9%) was recorded in the patients with preeclampsia and is statistically with relation to maternal and gestational age and parity.
Objective: The purpose of this study was to evaluate the foetal and mother outcomes of attempting a vaginal delivery following a prior caesarean section. Study Design: Cross-sectional study Place and Duration: Gynaecology and Obstetrics Department Ghulam Mohammad Maher Medical College Sukker. January 2022-December 2022 Methods: Total 50 pregnant females had gestational age 37-42 weeks and had history of one c-section were included. During labor, the mother and baby were closely monitored for indicators of fetal distress, including changes in heart rate, discomfort, and tenderness in the lower abdomen. Written informed consent was obtained using a consent form, and data was collected using pre-designed Performa. Complications among all females were recorded. SPSS 23.0 was used to analyze all data. Results: There were 30 (60%) females had age 18-30 years, 16 (32%) patients had age 31-40 years and 4 (8%) had age 41-45 years. Mean gestational age of the females was 39.17±14.63 weeks. Majority 35 (70%) females had poor socioeconomic status. 21 (42%) cases were educated. Out of the 50 pregnant females, 16 (32%) had vaginal deliveries and 34 (68%) had emergency cesarean section. Frequency of fetal distress was higher in cases of c-section as compared to vaginal deliveries with p value <0.005. As per maternal complications, wound infection and post op fever was higher in c-section while perineal tear and UTI was higher in vaginal deliveries. Post-partum hemorrhage was found in 7 cases, cases in c-section and 3 cases in vaginal deliveries. Frequency of feto-maternal favorable outcomes in vaginal deliveries were higher but difference was insignificant. Conclusion: This research shows that CS is associated with a higher risk of fetal distress, wound infection, and mother fever than vaginal delivery. Future morbidity from CS can be reduced if pregnant patients are urged to have vaginal births. Keywords: C-sectional, vaginal delivery, Complications, Favorable outcomes
Objective: To determine the impact of overactive bladder on health related quality of life (HRQOL). Study Design: Cross Sectional study. Setting: Department of Obstetrics and Gynaecology, Gambat Institute of Medical Sciences Gambat, Khairpur Sindh. Period: 1st November 2018 to 30th June 2019. Material & Methods: One Hundred forty nine women included who fulfilled inclusion criteria after taking inform consent. The questionnaire consisting of domain of general health perception, urinary incontinence, role limitation on physical, social & personal relationship, emotion with score was analyzed. Each question was carry 1 point as score .Score was analyzed further on percentage basis. Those who gain >33% were be labeled as impact of overactive bladder –ve patients. Finally data was analyzed on SPSS version 21. Results: The present study consisted of 145 subjects presented to the Department of Psychiatry, Services Hospital Lahore (both in and Out-patients). Over reactive bladder were matched on age, sex and socio-economic status & educational status. The age range of the total sample was 23-60 years. Mean age was 42.53 + 11.69. The duration of symptoms range of the total sample was 09-20 years. Mean duration was 16.7 + 5.6. The prevalence of over reactive bladder (OAB) syndrome were found 21%, respectively. The age were divided in to four classification age groups 17(11.7%) under the age of <30years, 31(21.4%) under the age of 31-40 years, 85(58.6%) found under the age of (58.6%) & 41-50 Years of age 85(58.6%) Women constitute the largest age groups. Out of 145 Women 68(46.9%) were Illiterate, 48(33.1%) were literate up to intermediate, 29(20%), took graduation education. The distribution of income classes of women 61(42.06%) belong to low class, 65(44.84%) belong to middle class and only 19(13.10%) belong to upper class. The parity distributions were revealed that most of the 78(53.7%) women had multiparty. Stratification of confounding variable for effect modifier Age & parity were found to be significantly associated with over reactive bladder syndrome. Again Stratification of confounding variable for effect modifier socio economic status & education status are not found significantly associated with over reactive bladder syndrome & P –Value were not found significantly associated with OAB P>0.05. Conclusion: We concluded incidence of overactive bladder in the female is almost similar and associated with increasing your age. Patients of OAB are under-diagnosed and under-treated. This patient can benefit from standard tests.
Objective: To estimate the frequency of abnormal cervical cytology detected by Pap smear. Study Design: Cross Sectional Study. Setting: Department of Obstetrics and Gynaecology Gambat Institute of Medical Sciences Gambat, Khairpur Sindh. Period: November 2018 to June 2019. Material & Methods: A total of 160 women with the complaint of heavy vaginal discharge and moderate to servere lowere abdominal pain more than 6 weeks were included in this study. Per speculum examination of cervix was carried out with the help of cuscos speculum before PAP smear and finding were noted, After labeling the sample was sent to histopathology for cytological examination. Results: The average age of the patient’s was 37.68±7.46 years. Percentage of normal smears 10%, advance disease 1.3% and percentage of inflammatory smear is 63.8% while frequency of abnormal cervical cytology was observed in 25% in which CIN-1 was 12.5%, CIN-2 was 11.3% and CIN-3 was 1.3%. Conclusion: Our population have large numbers of undiagnosed cervical diseases. Therefore, Pap smear testing should be widely used throughout Pakistan to reduce the incidence of cervical cancer.
Objectives: To find out the risk factors and their effects on mother and fetus in pregnancy with thrombocytopenia. Study Design: Cross sectional study. Setting: Department of Obstetrics and Gynaecology at Liaquat University Hospital Hyderabad. Period: Six months (1st July 2016 to 31st December 2016). Material and Methods: Total 96 patients with gestational age >24 weeks having platelet count below 150X109/L were included in the study. Patients admitted throughout patient clinic department of obstetrics & Gynecology at Liaqat University Hospital. Those patients having platelet count below 150X109/L were registered for study. Proforma filled which include Patients demographics details, gestational age, complete blood count (Having platelet count) other important investigations like coagulation profile (PT, APTT), Ultrasound and LFT noted in proforma SPSS version used for analysis. Descriptive statics were calculated frequency and percentages were drawn for the study. Results: Risk factors related to thrombocytopenia included PIH18 (18.8%), preeclampsia 14(14.6%), eclampsia 10(10.3%), HELLP Syndrome 6(6.3%), Viral Hepatitis 12(12.5%) and in 36(37.5%) no risk factors was found. Maternal complication were placental abruption21 (21.8%) post partam hemorrhage 14(14.6%). 7(7.3%) were transferred to ICU and 02(2.1%) maternal death was seen. Fetal outcome include low Apgar score of <6 in 17(17.7%), low birth weight 16(16.7%) and NICU admission 11(11.5%). Conclusion: Thrombocytopenia is a common finding in pregnancy careful diagnosis is important to distinguish serious causes from mild then to manage mother and fetus appropriately. Thrombocytopenia in pregnancy is associated with adverse maternal and fetal outcome in significant number of pregnant woman.
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