Recently we treated a 24-year-old female IHSS patient by mitral valve replacement, using a porcine xenograft valve. Following surgery, clinical manifestations improved markedly and postoperative cardiac catheterization revealed that the pressure gradient between left ventricle and aorta had dropped to a minimum compared with the pre-operative value of 104 mmHg and end-diastolic pressure of the left ventricle had returned to normal level.
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