We present a novel implementation of the pairwise DNA sequence alignment problem other than the Dynamic programming solution presented by Smith Waterman Algorithm. The proposed implementation uses CUDA; the parallel computing platform and programming model invented by NVIDIA. The main idea of the proposed implementation is assigning different nucleotide weights then merging the subsequences of match using the GPU Architecture according to predefined rules to get the optimum local alignment. We parallelize the whole solution for the pairwise DNA sequence alignment using CUDA and compare the results against a similar semi-parallelized solution and a traditional SmithWaterman implementation on traditional processors; Experimental results demonstrate a considerable reduction in the running time.
Most of the MAC protocols proposed for the wireless sensor networks (WSN) assume sensor nodes to be static and therefore they usually fail or provide very bad network performance in mobile sensor networks. Since WSN mobile applications have become popular nowadays, there is a need for MAC protocols that consider mobility. In this paper, we propose a mobility-aware MAC protocol for WSN that can work with satisfactory performance in both stationary and mobile sensor networks. Furthermore, most of the WSN mobile applications are considered critical ones (e.g. a patient assistance system which monitors patients' health via wearable bio-sensors). Such applications require very quick responses. So, in addition to handling mobility, the proposed MAC protocol considers the problem of latency as well. In summary, this paper proposes a WSN MAC protocol (MD-SMAC) that is considered to be mobility-aware, delay-sensitive and provides satisfactory level of energy efficiency. In addition, we study the performance of the proposed MD-SMAC protocol by simulating it using the NS-2 simulator and comparing it to other WSN MAC protocols. The results show that the MD-SMAC protocol outperforms other existing WSN MAC protocols in terms of mobility-handling, delay-reduction, and energy-efficiency in scenarios involving mobile sensors.
The Session Initiation Protocol (SIP) is one of the most common protocols that are used for signaling function in Voice over IP (VoIP) networks. The SIP protocol is very popular because of its flexibility, simplicity, and easy implementation, so it is a target of many attacks. In this paper, we propose a new system to detect the Denial of Service (DoS) attacks (i.e. malformed message and invite flooding) and Spam over Internet Telephony (SPIT) attack in the SIP based VoIP networks using a linear Support Vector Machine with l1 regularization (i.e. l1-SVM) classifier. In our approach, we project the SIP messages into a very high dimensional space using string based n-gram features. Hence, a linear classifier is trained on the top of these features. Our experimental results show that the proposed system detects malformed message, invite flooding, and SPIT attacks with a high accuracy. In addition, the proposed system outperformed other systems significantly in the detection speed.
Table of contents O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic medicine Ahmed Rebai O15 E-GRASP: an interactive database and web application for efficient analysis of disease-associated genetic information Sajjad Karim, Hend F Nour Eldin, Heba Abusamra, Elham M Alhathli, Nada Salem, Mohammed H Al-Qahtani, Sudhir Kumar O16 The supercomputer facility “AZIZ” at KAU: utility and future prospects Hossam Faheem O17 New research into the causes of male infertility Ashok Agarwa O18 The Klinefelter syndrome: recent progress in pathophysiology and management Eberhard Nieschlag, Joachim Wistuba, Oliver S. Damm, Mohd A. Beg, Taha A. Abdel-Meguid, Hisham A. Mosli, Osama S. Bajouh, Adel M. Abuzenadah, Mohammed H. Al-Q...
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