Surface antigens on melanoma cells were studied with an MIF method applied for monolayers of cultured cells. Human sera were used with indirect immunofluorescence. Preparations were fixed in methanol after staining. Reactions of sera with antibodies against trasplantation antigens displayed a fine granular fluorescence. This appearance was abolished by absorptions with pooled tonsilar lymphocytes. Melanoma patients' sera free from antibodies against transplantation antigens exhibited a coarse patchy fluorescence reaction. Melanoma patients' sera with antibodies against transplantation antigens yielded the second type of MIF reaction after absorptions with normal lymphocytes whereas further absorptions with melanoma line suspensions effectively removed all antibody reactivity...
The development of atheromatosis in the carotid artery of hypercholesterolaemic rabbits after x-irradiation is described. Irradiation with 500-3000 r causes infiltration of fat, deposition of lipophages and structural changes in the arterial wall within a few weeks. t This work was carried out under a research contract with the International Atomic Energy Agency. Int J Radiat Biol Downloaded from informahealthcare.com by York University Libraries on 11/21/14 For personal use only.
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