Background: Atrophic chronic gastritis (ACG) is a preneoplastic condition of gastric carcinoma.Numerous studies have shown anxiety and depression can affect gastrointestinal function, which may promote gastrointestinal disorders development and progression. Thus, we hypothesized that anxiety and depression may enhance the development and progression of ACG. In this study, we aimed to analyse risk factors for anxiety and depression in ACG patients and integrate these risk factors to construct an effective clinical prediction model.
Methods:In total, 118 ACG patients were included from July 2021 to May 2022. Anxiety and depression were assessed utilizing the Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9). Data were collected on demographic characteristics, lifestyle, and dietary habits. Risk factors for anxiety and depression were explored with univariate analysis and multivariate stepwise logistic regression, and risk prediction models were built.Results: Among 118 ACG patients, 36.4% had anxiety, 25.4% had depression, and 21.2% had both anxiety and depression. Poor sleep quality [odd ratio (OR) 4.32, 95% confidence interval (CI): 1.60-11.65, P=0.004] was positively associated with risk of anxiety, while smoking (OR 0.15, 95% CI: 0.03-0.68, P=0.014) and weekly exercise time (OR 0.89, 95% CI: 0.79-0.99, P=0.037) were negatively associated with risk of anxiety.The area under the receiver operating characteristic (ROC) curve was 80.3%, 95% CI: [0.722-0.885].
Six novel Cd(ii) complexes based 1-(benzotriazole-1-methyl)-2- propylimidazole are synthesized. These complexes share common features such as they all contain inorganic SBUs and have a high degree of dependence on the corresponding counter anions.
A new luminescent coordination polymer, namely [Zn(pzdc)(AmTAZ)] n (1 H 2 pzdc D pyrazine-2,3-dicarboxylic acid, AmTAZ D 3-amino-1,2,4-triazole), has been successfully synthesized under hydrothermal conditions. Single-crystal X-ray analysis reveals that 1 is a two-dimensional (2D) layered structure with the terminal AmTAZ ligands dangling up and down the layer. Finally, these 2D layers are further extended into a three-dimensional (3D) supramolecular framework through intermolecular hydrogen bonds.
The rational selection of ligands is vitally important in the construction of coordination complexes. Two novel Zn complexes, namely bis(acetato-κO)bis[1-(1H-benzotriazol-1-ylmethyl)-2-propyl-1H-imidazole-κN]zinc(II) monohydrate, [Zn(CHN)(CHO)]·HO, (1), and bis(azido-κN)bis[1-(1H-benzotriazol-1-ylmethyl)-2-propyl-1H-imidazole-κN]zinc(II), [Zn(CHN)(N)], (2), constructed from the asymmetric multidentate imidazole ligand, have been synthesized under mild conditions and characterized by elemental analyses, IR spectroscopy and single-crystal X-ray diffraction analysis. Both complexes exhibit a three-dimensional supramolecular network directed by different intermolecular interactions between discrete mononuclear units. The complexes were also investigated by fluorescence and thermal analyses. The experimental results show that (1) is a promising fluorescence sensor for detecting Fe ions and (2) is effective as an accelerator of the thermal decomposition of ammonium perchlorate.
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